Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | PAM | P19021 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | KLK7 | P49862 | 2/20 | 0.39 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
| ▸ | CPA1 | P15085 | 2/20 | 0.39 |
| ▸ | CPB1 | P15086 | 1/20 | 0.39 |
| ▸ | CPA3 | P15088 | 1/20 | 0.39 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18671086 | 0.80 | TSHR (0.67) | TSHRALDH1A1MAPK1L3MBTL1PAM | |
| SCHEMBL11025357 | 0.79 | TSHR (0.56) | TSHRALDH1A1MAPK1L3MBTL1PAM | |
| SCHEMBL8964976 | 0.79 | TSHR (0.56) | TSHRALDH1A1MAPK1L3MBTL1PAM | |
| SCHEMBL8964840 | 0.75 | TSHR (0.55) | TSHRALDH1A1MAPK1L3MBTL1PAM | |
| SCHEMBL8965109 | 0.73 | TSHR (0.49) | TSHRALDH1A1MAPK1L3MBTL1PAM | |
| SCHEMBL10404918 | 0.73 | ALDH1A1 (0.55) | TSHRALDH1A1MAPK1L3MBTL1PAM | |
| SCHEMBL873430 | 0.73 | TSHR (1.00) | TSHRALDH1A1MAPK1L3MBTL1PAM | |
| SCHEMBL4363372 | 0.73 | TSHR (0.67) | TSHRALDH1A1MAPK1L3MBTL1PAM | |
| SCHEMBL28112015 | 0.73 | TSHR (0.67) | TSHRALDH1A1MAPK1L3MBTL1PAM | |
| SCHEMBL14332763 | 0.73 | TSHR (0.67) | TSHRALDH1A1MAPK1L3MBTL1PAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2007126378-A | METHOD FOR PRODUCING OPTICALLY ACTIVE NITROGEN-CONTAINING COMPOUND | KANTO CHEM CO INC | 2007-05-24 | — | — | JP | disclosed |