Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | PKM | P14618 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.67 |
| ▸ | AR | P10275 | 1/20 | 0.66 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.66 |
| ▸ | IL1RN | P18510 | 1/20 | 0.66 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.66 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.62 |
| ▸ | CA12 | O43570 | 1/20 | 0.61 |
| ▸ | CA1 | P00915 | 1/20 | 0.61 |
| ▸ | CA2 | P00918 | 1/20 | 0.61 |
| ▸ | CA9 | Q16790 | 1/20 | 0.61 |
| ▸ | GPR27 | Q9NS67 | 4/20 | 0.60 |
| ▸ | AVPR2 | P30518 | 3/20 | 0.60 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.59 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.59 |
| ▸ | CDK1 | P06493 | 1/20 | 0.59 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.59 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2567685 | 0.93 | NR1H3 (0.71) | KMT2APKMMEN1ALDH1A1AR | |
| SCHEMBL14601685 | 0.91 | MEN1 (0.65) | KMT2AMEN1ALDH1A1ARNR1H3 | |
| SCHEMBL12010881 | 0.88 | MEN1 (0.68) | KMT2AMEN1ALDH1A1ARNR1H3 | |
| SCHEMBL12947549 | 0.85 | KMT2A (0.61) | KMT2APKMMEN1ALDH1A1AR | |
| SCHEMBL7577535 | 0.84 | CA1 (0.65) | KMT2APKMMEN1ALDH1A1AR | |
| SCHEMBL7588697 | 0.84 | PTGES2 (0.74) | KMT2AMEN1CA1CA2PTGES2 | |
| SCHEMBL12010912 | 0.83 | NR1H3 (0.68) | KMT2AMEN1ALDH1A1ARNR1H3 | |
| SCHEMBL18031173 | 0.83 | UQCRB (0.71) | KMT2AMEN1ARERAP1NR1H3 | |
| SCHEMBL7571036 | 0.83 | CES1 (0.73) | KMT2AMEN1ALDH1A1ARCA1 | |
| SCHEMBL4573249 | 0.83 | KMT2A (0.71) | KMT2AMEN1ALDH1A1ARKEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108822002-B | Method for synthesizing N-aryl sulfonamide under assistance of ultrasonic waves | 中南大学 | 2020-05-05 | — | — | CN | disclosed |
| CN-108822002-A | A kind of method of ultrasonic wave added synthesis N- aryl sulfonic acid amides | 中南大学 | 2018-11-16 | — | — | CN | disclosed |
| EP-1239852-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | Arrow Therapeutics Limited (GB) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001028537-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | ARROW THERAPEUTICS LIMITED (GB) | 2001-04-26 | — | — | WO | disclosed |