Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5597605 | 0.89 | — | — | |
| SCHEMBL6301079 | 0.87 | — | — | |
| SCHEMBL406721 | 0.84 | — | — | |
| SCHEMBL3445939 | 0.82 | — | — | |
| SCHEMBL10613510 | 0.80 | TSHR (0.39) | ALDH1A1TSHR | |
| SCHEMBL8436725 | 0.80 | ALDH1A1 (0.46) | ALDH1A1HCAR2TSHR | |
| SCHEMBL2140364 | 0.79 | — | — | |
| SCHEMBL23912021 | 0.77 | — | — | |
| SCHEMBL3292271 | 0.77 | — | — | |
| SCHEMBL919091 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023215521-A2 | HALIDE-FREE AMMONIUM SILANES | TOPIKOS SCIENTIFIC, INC. (US) | 2023-11-09 | — | — | WO | disclosed |
| US-7268262-B2 | Method for recovering trans-1,2-dichloroethene | PPG INDUSTRIES OHIO, INC. (US) | 2007-09-11 | — | — | US | disclosed |
| EP-1740519-A1 | METHOD FOR RECOVERING TRANS-1,2-DICHLOROETHENE | PPG Industries Ohio, Inc. (US) | 2007-01-10 | — | — | EP | disclosed |
| WO-2005110954-A1 | METHOD FOR RECOVERING TRANS-1,2-DICHLOROETHENE | PPG INDUSTRIES OHIO, INC. (US) | 2005-11-24 | — | — | WO | disclosed |
| US-20050245775-A1 | Method for recovering trans-1,2-dichloroethene | EAGLE US 2 LLC | 2005-11-03 | — | — | US | disclosed |
| EP-1521732-A1 | METHOD OF STABILIZING TRICHLOROETHANE DURING PRODUCTION | PPG Industries Ohio, Inc. (US) | 2005-04-13 | — | — | EP | disclosed |
| US-20040030203-A1 | Method of stabilizing trichloroethane during production | PPG INDUSTRIES OHIO, INC. | 2004-02-12 | — | — | US | disclosed |
| WO-2004007409-A1 | METHOD OF STABILIZING TRICHLOROETHANE DURING PRODUCTION | PPG INDUSTRIES OHIO, INC. (US) | 2004-01-22 | — | — | WO | disclosed |
| US-6150573-A | Concurrent production of trichloroethane isomers | PPG INDUSTRIES OHIO, INC. (US) | 2000-11-21 | — | — | US | disclosed |
| US-5382727-A | Free radical chlorination of 1,1-dichloroethane | PPG INDUSTRIES, INC. (US) | 1995-01-17 | — | — | US | disclosed |
| US-5315052-A | Concurrent production of trichloroethane isomers | PPG INDUSTRIES, INC. (US) | 1994-05-24 | — | — | US | disclosed |
| US-5298646-A | Introducing molecular chlorine to stripping zone, contacting ethyl chloroformate in rectifying zone, condensation, refluxing, removal of gaseous phase | PPG INDUSTRIES, INC. (US) | 1994-03-29 | — | — | US | disclosed |
| US-5051536-A | Using a free radical catalyst to form cis-, trans-isomers | PPG INDUSTRIES, INC. (US) | 1991-09-24 | — | — | US | disclosed |
| WO-1991002708-A1 | METHOD FOR ISOMERIZING 1,2-DICHLOROETHENE | PPG INDUSTRIES, INC. (US) | 1991-03-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040030203-A1 | Method of stabilizing trichloroethane during production | TTPA, CBR1, TCEA1 | ALDH1A1 460/4885KEAP1 84/4885NFE2L2 22/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.