Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.41 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28355498 | 0.88 | TSHR (0.55) | TSHRMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL5597695 | 0.87 | ALDH1A1 (0.53) | TSHRALDH1A1HSD17B10GAAL3MBTL1 | |
| SCHEMBL5597642 | 0.84 | TSHR (0.55) | TSHRMEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL28637275 | 0.84 | TSHR (0.47) | TSHRMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL8101670 | 0.83 | TSHR (0.50) | TSHRMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL27799475 | 0.83 | TSHR (0.50) | TSHRMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL5597611 | 0.83 | TSHR (0.56) | TSHRMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL3306441 | 0.83 | ALDH1A1 (0.42) | TSHRKMT2AALDH1A1HSD17B10HTT | |
| SCHEMBL2825239 | 0.83 | TSHR (0.69) | TSHRMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL5597694 | 0.83 | ALDH1A1 (0.54) | TSHRMEN1KMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0765304-B2 | METHOD OF PREPARING ALPHA-METHOXYIMINOCARBOXYLIC ACID METHYLAMIDES, AND INTERMEDIATES USED IN THE METHOD | BAYER CROPSCIENCE AG (DE) | 2007-08-22 | — | — | EP | claimed |
| CN-1406221-A | Process for preparing alpha-ketocarboxylic acid derivatives | KOREA RES INST CHEM TECH (KR) | 2003-03-26 | — | — | CN | claimed |
| EP-1097917-B1 | Preparing method of alpha-ketocarboxylic acid derivatives | KOREA RES INST CHEM TECH (KR) | 2003-02-12 | — | — | EP | claimed |
| EP-1097917-A1 | Preparing method of alpha-ketocarboxylic acid derivatives | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2001-05-09 | — | — | EP | claimed |
| WO-2001030741-A1 | PREPARING METHOD OF ALPHA-KETOCARBOXYLIC ACID DERIVATIVES | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2001-05-03 | — | — | WO | claimed |
| US-6124493-A | Process for the preparation of o-chloromethyl-phenylglyoxylic acid derivatives | NOVARTIS FINANCE CORPORATION (US) | 2000-09-26 | — | — | US | disclosed |
| US-6121476-A | Process for preparing dithiocarbonimide derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-09-19 | — | — | US | disclosed |
| EP-0811612-B1 | Process for preparing dithiocarbonimide derivatives | SUMITOMO CHEMICAL CO (JP) | 1999-03-03 | — | — | EP | disclosed |
| US-5756811-A | Process for the preparation of o-chloromethyl-phenylglyoxylic acid derivatives | NOVARTIS CORPORATION (US) | 1998-05-26 | — | — | US | disclosed |
| CN-1169989-A | Process for preparing dithiocarbonimide derivatives | SUMITOMO CHEMICAL CO (JP) | 1998-01-14 | — | — | CN | disclosed |
| EP-0811612-A1 | Process for preparing dithiocarbonimide derivatives | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1997-12-10 | — | — | EP | disclosed |