SCHEMBL2825239

SCHEMBL2825239

CCOC(=O)c1ccccc1CCl

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.69
ALDH1A1 P00352 3/20 0.59
HSD17B10 Q99714 3/20 0.59
CDC25B P30305 2/20 0.50
KDM4E B2RXH2 2/20 0.48
TDP1 Q9NUW8 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
KMT2A Q03164 2/20 0.47
CYP3A4 P08684 2/20 0.47
LMNA P02545 1/20 0.47
CDC25A P30304 1/20 0.47
CDC25C P30307 1/20 0.47
MEN1 O00255 1/20 0.47
USP2 O75604 1/20 0.47
CYP1A2 P05177 1/20 0.47
MAPT P10636 1/20 0.47
CYP2C9 P11712 1/20 0.47
ALOX15 P16050 1/20 0.47
CYP2C19 P33261 1/20 0.47
MAPK10 P53779 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL578128 0.87 TSHR (0.77) TSHRALDH1A1HSD17B10CDC25BKDM4E
SCHEMBL6596574 0.86 ALDH1A1 (0.71) TSHRALDH1A1HSD17B10KDM4ETDP1
SCHEMBL7211498 0.85 TSHR (0.47) TSHRALDH1A1HSD17B10KDM4ETDP1
SCHEMBL7669334 0.84 TSHR (0.71) TSHRALDH1A1HSD17B10CDC25BKDM4E
SCHEMBL7670783 0.84 TSHR (0.71) TSHRALDH1A1HSD17B10CDC25BKDM4E
SCHEMBL22532100 0.83 TSHR (0.56) TSHRALDH1A1HSD17B10CDC25BKDM4E
SCHEMBL5679381 0.83 TSHR (0.73) TSHRALDH1A1HSD17B10KDM4ETDP1
SCHEMBL5597833 0.83 TSHR (0.50) TSHRALDH1A1HSD17B10TDP1L3MBTL1
SCHEMBL27781655 0.83 ALDH1A1 (0.47) TSHRALDH1A1HSD17B10KDM4ETDP1
SCHEMBL1492404 0.83 TSHR (0.65) TSHRALDH1A1HSD17B10CDC25BKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109535662-B 3D printing material and preparation method thereof 福州万象三维电子科技有限公司 2021-03-19 CN claimed
CN-111334023-A Degradable 3D printing material and preparation method thereof 黎明职业大学 2020-06-26 CN claimed
CN-109535662-A A kind of 3D printing material and preparation method thereof 福州万象三维电子科技有限公司 2019-03-29 CN claimed
CN-109486162-A Degradable 3D printing material and preparation method thereof 福州万象三维电子科技有限公司 2019-03-19 CN claimed
CN-102443018-B Fluorescence-labeled O6-benzyl guanine and preparation and application thereof UNIV ZHEJIANG 2014-09-10 CN claimed
CN-102443018-A fluorescently labeled O6-benzylguanine, preparation and use thereof UNIV ZHEJIANG 2012-05-09 CN claimed
EP-3604310-B1 CDC-7-INHIBITOR COMPOUNDS AND USE THEREOF FOR THE TREATMENT OF NEUROLOGICAL CONDITIONS CONSEJO SUPERIOR INVESTIGACION (ES) 2024-09-11 EP disclosed
CN-113372215-B Novel esterification method for synthesizing p-halomethyl benzoate 吉林大学 2024-05-24 CN disclosed
CN-117062811-A 3- (1-oxo-isoindolin-2-yl) piperidine-2, 6-dione derivatives and medical use thereof 诺华股份有限公司 2023-11-14 CN disclosed
US-11446304-B2 CDC-7-inhibitor compounds and use thereof for the treatment of neurological conditions CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (ES) 2022-09-20 US disclosed
CN-109535662-B 3D printing material and preparation method thereof 福州万象三维电子科技有限公司 2021-03-19 CN disclosed
CN-109535662-B 3D printing material and preparation method thereof 福州万象三维电子科技有限公司 2021-03-19 CN disclosed
CN-111334023-A Degradable 3D printing material and preparation method thereof 黎明职业大学 2020-06-26 CN disclosed
US-4835312-A Production process of N-substituted amide compounds MITSUI CHEMICALS, INCORPORATED (JP) 1989-05-30 US disclosed
US-4337264-A ANALGESICS, ANTIINFLAMMATORY AGENTS AND FUNGICIDES CIBA-GEIGY CORPORATION (US) 1982-06-29 US disclosed
US-4316850-A ANTINFLAMMATORY AGENTS CIBA-GEIGY CORPORATION (US) 1982-02-23 US disclosed
US-4264619-A Tertiary aminoacids CIBA-GEIGY CORPORATION (US) 1981-04-28 US disclosed
US-4163788-A ANTIINFLAMMATORY CIBA-GEIGY CORPORATION (US) 1979-08-07 US disclosed
US-4126691-A ANTIINFLAMMATORY CIBA-GEIGY CORPORATION (US) 1978-11-21 US disclosed
US-3997669-A ANTIINFLAMMATORY CIBA-GEIGY CORPORATION (US) 1976-12-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11446304-B2 CDC-7-inhibitor compounds and use thereof for the treatment of neurological conditions CDC7, TARDBP, CDC14A TSHR 4701/4885ALDH1A1 4331/4885HSD17B10 4034/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.