Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.39 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.33 |
| ▸ | PRKCA | P17252 | 1/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.32 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.32 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14418633 | 1.00 | KMT2A (0.42) | KMT2AMEN1CYP2D6CYP2C19SLC22A2 | |
| SCHEMBL4137129 | 0.75 | KMT2A (0.44) | KMT2AMEN1CYP2D6CYP2C19SLC22A2 | |
| SCHEMBL3813603 | 0.73 | KMT2A (0.48) | KMT2AMEN1CYP2D6CYP2C19SLC22A2 | |
| SCHEMBL14055077 | 0.73 | SLC22A2 (0.41) | KMT2AMEN1CYP2D6CYP2C19SLC22A2 | |
| SCHEMBL9670646 | 0.71 | KMT2A (0.42) | KMT2AMEN1CYP2D6CYP2C19SLC22A2 | |
| SCHEMBL5301476 | 0.71 | SLC22A2 (0.50) | KMT2AMEN1CYP2D6CYP2C19SLC22A2 | |
| SCHEMBL14695859 | 0.71 | SLC22A2 (0.50) | KMT2AMEN1CYP2D6CYP2C19SLC22A2 | |
| SCHEMBL4946866 | 0.71 | SLC22A2 (0.50) | KMT2AMEN1CYP2D6CYP2C19SLC22A2 | |
| SCHEMBL17347044 | 0.69 | KMT2A (0.65) | KMT2AMEN1CYP2D6CYP2C19SLC22A2 | |
| SCHEMBL4136815 | 0.68 | KMT2A (0.43) | KMT2AMEN1CYP2D6CYP2C19SLC22A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7265249-B2 | Enantioselective alpha-fluorination of aldehydes using chiral organic catalysts | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2007-09-04 | — | — | US | disclosed |
| US-20060189830-A1 | Enantioselective alpha-fluorination of aldehydes using chiral organic catalysts | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2006-08-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060189830-A1 | Enantioselective alpha-fluorination of aldehydes using chiral organic catalysts | ALDH3A1, ALDH1A1, POLL | KMT2A 924/4885MEN1 2018/4885CYP2D6 3464/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.