Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.50 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.50 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.50 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | GFER | P55789 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9779048 | 0.98 | CHRNB2 (0.53) | CHRNB2CHRNB4CHRNA3CHRNA4ALDH1A1 | |
| SCHEMBL1903553 | 0.82 | ALDH1A1 (0.62) | CHRNB2CHRNB4CHRNA3CHRNA4ALDH1A1 | |
| SCHEMBL9779133 | 0.82 | ALDH1A1 (0.54) | ALDH1A1KMT2AMAPTRAB9AHTT | |
| SCHEMBL9779110 | 0.81 | ALDH1A1 (0.65) | CHRNB2CHRNB4CHRNA3CHRNA4ALDH1A1 | |
| SCHEMBL9381303 | 0.78 | ALDH1A1 (0.69) | ALDH1A1KMT2AGFERMAPTSLC6A3 | |
| SCHEMBL3928222 | 0.76 | ALDH1A1 (0.69) | ALDH1A1KMT2AGFERNPC1KDM4E | |
| SCHEMBL13092866 | 0.76 | HPGD (0.62) | ALDH1A1KMT2AKDM4EMAPT | |
| Hydrochloric Acid SCHEMBL9851658 | 0.75 | ALDH1A1 (0.70) | ALDH1A1KMT2AGFERNPC1KDM4E | |
| SCHEMBL14380085 | 0.73 | L3MBTL3 (0.39) | ALDH1A1KMT2AKDM4E | |
| SCHEMBL31093170 | 0.73 | SLC6A4 (0.69) | ALDH1A1KMT2AGFERMAPTSLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020227618-A2 | CONVERGENT LIQUID PHASE SYNTHESES OF OLIGONUCLEOTIDES | BIOGEN MA INC. (US) | 2020-11-12 | — | — | WO | disclosed |
| US-7222650-B2 | Tire with a tread comprising a rubbery polymer of a functionalized monomer | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2007-05-29 | — | — | US | disclosed |
| US-7041761-B2 | Functionalized monomers for synthesis of rubbery polymers | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2006-05-09 | — | — | US | disclosed |
| US-6995224-B2 | Functionalized monomers for synthesis of rubbery polymers | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2006-02-07 | — | — | US | disclosed |
| US-6936669-B2 | Functionalized monomers for synthesis of rubbery polymers | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2005-08-30 | — | — | US | disclosed |
| US-6933358-B2 | Reacting secordary amine with 2,3-dihalopropene forming monomer | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2005-08-23 | — | — | US | disclosed |
| US-20050131181-A1 | FUNCTIONALIZED MONOMERS FOR SYNTHESIS OF RUBBERY POLYMERS | THE GOODYEAR TIRE & RUBBER COMPANY | 2005-06-16 | — | — | US | disclosed |
| US-6901982-B2 | Functionalized monomers for synthesis of rubbery polymers | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2005-06-07 | — | — | US | disclosed |
| US-20050049377-A1 | Functionalized monomers for synthesis of rubbery polymers | THE GOODYEAR TIRE & RUBBER COMPANY | 2005-03-03 | — | — | US | disclosed |
| US-20050006014-A1 | Functionalized monomers for synthesis of rubbery polymers | THE GOODYEAR TIRE & RUBBER COMPANY | 2005-01-13 | — | — | US | disclosed |
| US-6812307-B2 | FORMING FILLER COMPATIBLE MATERIALS; SOLUTION COPOLYMERIZING AT LEAST CONJUGATED DIOLEFIN AND AMINE FUNCTIONALIZED STYRENE MONOMER | THE GOODYEAR TIRE & RUBBER COMPANY | 2004-11-02 | — | — | US | disclosed |
| US-20040122194-A1 | Functionalized monomers for synthesis of rubbery polymers | THE GOODYEAR TIRE & RUBBER COMPANY | 2004-06-24 | — | — | US | disclosed |
| US-20040122224-A1 | Functionalized monomers for synthesis of rubbery polymers | THE GOODYEAR TIRE & RUBBER COMPANY | 2004-06-24 | — | — | US | disclosed |
| US-6753447-B2 | REACTING SECONDARY AMINE WITH 2,3- DIHALOPROPENE TO PRODUCE A VINYL HALIDE CONTAINING CYCLIC TERTIARY AMINE; REACTING WITH VINYL MAGNESIUM HALIDE IN POLAR SOLVENT | THE GOODYEAR TIRE & RUBBER COMPANY | 2004-06-22 | — | — | US | disclosed |
| US-20040116635-A1 | Functionalized monomers for synthesis of rubbery polymers | GOODYEAR TIRE & RUBBER COMPANY, THE | 2004-06-17 | — | — | US | disclosed |
| US-20040063884-A1 | Functionalized monomers for synthesis of rubbery polymers | THE GOODYEAR TIRE & RUBBER COMPANY | 2004-04-01 | — | — | US | disclosed |
| US-20040048972-A1 | Functionalized monomers for synthesis of rubbery polymers | GOODYEAR TIRE & RUBBER COMPANY, THE | 2004-03-11 | — | — | US | disclosed |
| US-20040044157-A1 | Functionalized monomers for synthesis of rubbery polymers | GOODYEAR TIRE & RUBBER COMPANY, THE | 2004-03-04 | — | — | US | disclosed |
| US-20040044202-A1 | Functionalized monomers for synthesis of rubbery polymers | THE GOODYEAR TIRE & RUBBER COMPANY | 2004-03-04 | — | — | US | disclosed |
| US-6693160-B1 | FREE RADICAL COPOLYMERS OF CONJUGATED DIOLEFIN AND NITROGEN HETEROCYCLE FUNCTIONALIZED MONOMERS; LOW HYSTERESIS; FILLER COMPATIBILITY | THE GOODYEAR TIRE & RUBBER COMPANY | 2004-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040044202-A1 | Functionalized monomers for synthesis of rubbery polymers | PRMT1, DDR2, DNMT3A | CHRNB2 2334/4885CHRNB4 3245/4885CHRNA3 1911/4885 |
| US-20050006014-A1 | Functionalized monomers for synthesis of rubbery polymers | RDX, DPY30, COIL | CHRNB2 3384/4885CHRNB4 2561/4885CHRNA3 2999/4885 |
| US-20040063884-A1 | Functionalized monomers for synthesis of rubbery polymers | RDX, DPY30, RIF1 | CHRNB2 3060/4885CHRNB4 2545/4885CHRNA3 2861/4885 |
| US-20040122224-A1 | Functionalized monomers for synthesis of rubbery polymers | PRMT1, DDR2, DNMT3A | CHRNB2 2334/4885CHRNB4 3245/4885CHRNA3 1911/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.