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Sugi Predict / Compounds / SCHEMBL559795

SCHEMBL559795

SCHEMBL559795

O=C(O)/C(CC(O)(Cc1ccccc1)C(=O)O)=N/O

nearest known ligand 0.54

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ CTBP2 P56545 13/20 0.54
▸ SMN1; SMN2 Q16637 1/20 0.43
▸ HIF1A Q16665 1/20 0.43
▸ FDPS P14324 1/20 0.39
▸ CYP1A2 P05177 4/20 0.38
▸ CYP2C19 P33261 2/20 0.38
▸ CYP2C9 P11712 1/20 0.38
▸ SLC13A5 Q86YT5 1/20 0.38
▸ KDM4E B2RXH2 1/20 0.37
▸ MEN1 O00255 1/20 0.37
▸ LMNA P02545 1/20 0.37
▸ CYP2D6 P10635 1/20 0.37
▸ KMT2A Q03164 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL559796 1.00 CTBP2 (0.54) CTBP2SMN1; SMN2HIF1AFDPSCYP1A2
SCHEMBL559316 0.88 CTBP2 (0.57) CTBP2CYP1A2CYP2C19
SCHEMBL559315 0.88 CTBP2 (0.57) CTBP2CYP1A2CYP2C19
SCHEMBL559624 0.80 SMN1; SMN2 (0.48) SMN1; SMN2HIF1AFDPSCYP1A2CYP2C19
SCHEMBL7300860 0.79 SLC13A5 (0.56) SMN1; SMN2HIF1AFDPSCYP1A2CYP2C19
SCHEMBL419615 0.78 SMN1; SMN2 (0.59) SMN1; SMN2HIF1AFDPSCYP1A2CYP2C19
SCHEMBL10941763 0.78 SLC13A5 (0.54) SMN1; SMN2HIF1AFDPSCYP1A2CYP2C19
SCHEMBL9554595 0.76 SMN1; SMN2 (0.53) SMN1; SMN2HIF1AFDPSCYP1A2CYP2C19
SCHEMBL9554586 0.76 SMN1; SMN2 (0.53) SMN1; SMN2HIF1AFDPSCYP1A2CYP2C19
SCHEMBL559736 0.76 KMT2A (0.49) SMN1; SMN2HIF1AKDM4EMEN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120035373-A1 PROCESSES OF PRODUCING GLUTAMIC ACID COMPOUNDS AND PRODUCTION INTERMEDIATES THEREFORE AND NOVEL INTERMEDIATE FOR THE PROCESSES AJINOMOTO CO. INC (JP) 2012-02-09 — — US disclosed
US-7868187-B2 Processes of producing glutamic acid compounds and production intermediates therefore and novel intermediate for the processes AJINOMOTO CO., INC. (JP) 2011-01-11 — — US disclosed
US-20100105924-A1 PROCESSES OF PRODUCING GLUTAMIC ACID COMPOUNDS AND PRODUCTION INTERMEDIATES THEREFORE AND NOVEL INTERMEDIATE FOR THE PROCESSES AJINOMOTO CO. INC. (JP) 2010-04-29 — — US disclosed
US-7678925-B2 Processes of producing glutamic acid compounds and production intermediates therefore and novel intermediate for the processes AJINOMOTO CO., INC. (JP) 2010-03-16 — — US disclosed
US-20090259052-A1 PROCESSES OF PRODUCING GLUTAMIC ACID COMPOUNDS AND PRODUCTION INTERMEDIATES THEREFORE AND NOVEL INTERMEDIATE FOR THE PROCESSES AJINOMOTO CO. INC (JP) 2009-10-15 — — US disclosed
US-7390909-B2 Processes of producing glutamic acid compounds and production intermediates therefore and novel intermediate for the processes AJINOMOTO CO., INC. (JP) 2008-06-24 — — US disclosed
US-20080091032-A1 PROCESSES OF PRODUCING GLUTAMIC ACID COMPOUNDS AND PRODUCTION INTERMEDIATES THEREFORE AND NOVEL INTERMEDIATE FOR THE PROCESSES AJINOMOTO CO. INC (JP) 2008-04-17 — — US disclosed
US-7064219-B2 Processes of producing glutamic acid compounds and production intermediates therefore and novel intermediate for the processes AJINOMOTO CO., INC. (JP) 2006-06-20 — — US disclosed
US-20060074249-A1 Processes of producing glutamic acid compounds and production intermediates therefore and novel intermediate for the processes AJINOMOTO CO. INC (JP) 2006-04-06 — — US disclosed
US-20050004394-A1 Processes of producing glutamic acid compounds and production intermediates therefore and novel intermediate for the processes AJINOMOTO CO. IN (JP) 2005-01-06 — — US disclosed
EP-1466890-A1 PROCESSES FOR THE PREPARATION OF GLUTAMIC ACID COMPOUNDS AND INTERMEDIATES THEREOF AND NOVEL INTERMEDIATES USED IN THE PROCESSES Ajinomoto Co., Inc. (JP) 2004-10-13 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120035373-A1 PROCESSES OF PRODUCING GLUTAMIC ACID COMPOUNDS AND PRODUCTION INTERMEDIATES THEREFORE AND NOVEL INTERMEDIATE FOR THE PROCESSES GLUL, MON2, GRIK5 CTBP2 2823/4885SMN1; SMN2 2414/4885HIF1A 4218/4885
US-20050004394-A1 Processes of producing glutamic acid compounds and production intermediates therefore and novel intermediate for the processes GLUL, MON2, GRIK5 CTBP2 2823/4885SMN1; SMN2 2414/4885HIF1A 4218/4885
US-20080091032-A1 PROCESSES OF PRODUCING GLUTAMIC ACID COMPOUNDS AND PRODUCTION INTERMEDIATES THEREFORE AND NOVEL INTERMEDIATE FOR THE PROCESSES GLUL, MON2, GRIK5 CTBP2 2823/4885SMN1; SMN2 2414/4885HIF1A 4218/4885
US-20100105924-A1 PROCESSES OF PRODUCING GLUTAMIC ACID COMPOUNDS AND PRODUCTION INTERMEDIATES THEREFORE AND NOVEL INTERMEDIATE FOR THE PROCESSES GLUL, MON2, GRIK5 CTBP2 2823/4885SMN1; SMN2 2414/4885HIF1A 4218/4885
US-20060074249-A1 Processes of producing glutamic acid compounds and production intermediates therefore and novel intermediate for the processes GLUL, MON2, GRIK5 CTBP2 2823/4885SMN1; SMN2 2414/4885HIF1A 4218/4885
US-20090259052-A1 PROCESSES OF PRODUCING GLUTAMIC ACID COMPOUNDS AND PRODUCTION INTERMEDIATES THEREFORE AND NOVEL INTERMEDIATE FOR THE PROCESSES GLUL, MON2, GRIK5 CTBP2 2823/4885SMN1; SMN2 2414/4885HIF1A 4218/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.