Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.36 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5597746 | 0.88 | ALDH1A1 (0.36) | TSHRSMN1; SMN2NPC1ALDH1A1KMT2A | |
| SCHEMBL3306441 | 0.81 | ALDH1A1 (0.42) | TSHRALDH1A1KMT2AHTT | |
| SCHEMBL27471904 | 0.81 | KMT2A (0.41) | TSHRGAASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL5597694 | 0.81 | ALDH1A1 (0.54) | TSHRSMN1; SMN2NPC1ALDH1A1KMT2A | |
| SCHEMBL5597784 | 0.80 | HIF1A (0.46) | TSHRGAASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL5597674 | 0.79 | HTT (0.43) | TSHRGAASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL5597833 | 0.79 | TSHR (0.50) | TSHRGAASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL5598069 | 0.78 | MAPT (0.41) | TSHRSMN1; SMN2ALDH1A1KMT2AHSP90AB1 | |
| SCHEMBL8455285 | 0.77 | PRSS1 (0.42) | TSHRALDH1A1KMT2ACA2MAPT | |
| SCHEMBL5597695 | 0.76 | ALDH1A1 (0.53) | TSHRGAASMN1; SMN2ALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0765304-B2 | METHOD OF PREPARING ALPHA-METHOXYIMINOCARBOXYLIC ACID METHYLAMIDES, AND INTERMEDIATES USED IN THE METHOD | BAYER CROPSCIENCE AG (DE) | 2007-08-22 | — | — | EP | claimed |
| CN-1169989-A | Process for preparing dithiocarbonimide derivatives | SUMITOMO CHEMICAL CO (JP) | 1998-01-14 | — | — | CN | disclosed |