Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC10A6 | Q3KNW5 | 2/20 | 0.83 |
| ▸ | SLC10A2 | Q12908 | 1/20 | 0.83 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.83 |
| ▸ | METAP2 | P50579 | 2/20 | 0.67 |
| ▸ | GPR27 | Q9NS67 | 8/20 | 0.54 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.53 |
| ▸ | FLT1 | P17948 | 3/20 | 0.52 |
| ▸ | FLT4 | P35916 | 3/20 | 0.52 |
| ▸ | KDR | P35968 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.51 |
| ▸ | CCR9 | P51686 | 1/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6756862 | 0.91 | SLC10A6 (1.00) | SLC10A6SLC10A2SLC10A1METAP2GPR27 | |
| SCHEMBL7126120 | 0.90 | SLC10A6 (0.98) | SLC10A6SLC10A2SLC10A1METAP2GPR27 | |
| SCHEMBL5117189 | 0.89 | SLC10A6 (0.72) | SLC10A6SLC10A2SLC10A1METAP2GPR27 | |
| SCHEMBL5126770 | 0.86 | SLC10A6 (0.67) | SLC10A6SLC10A2SLC10A1GPR27AVPR2 | |
| SCHEMBL5115455 | 0.85 | SLC10A6 (0.88) | SLC10A6SLC10A2SLC10A1METAP2GPR27 | |
| SCHEMBL6861824 | 0.84 | SLC10A6 (0.87) | SLC10A6SLC10A2SLC10A1METAP2GPR27 | |
| SCHEMBL5597797 | 0.84 | SLC10A6 (0.75) | SLC10A6SLC10A2SLC10A1METAP2GPR27 | |
| SCHEMBL7118571 | 0.83 | SLC10A6 (0.85) | SLC10A6SLC10A2SLC10A1METAP2GPR27 | |
| SCHEMBL7213183 | 0.83 | SLC10A6 (0.73) | SLC10A6SLC10A2SLC10A1METAP2GPR27 | |
| SCHEMBL7116008 | 0.83 | SLC10A6 (0.85) | SLC10A6SLC10A2SLC10A1METAP2GPR27 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1815860-A2 | Phosphate transport inhibitors | GENZYME CORPORATION (US) | 2007-08-08 | — | — | EP | disclosed |
| EP-1815860-A2 | Phosphate transport inhibitors | GENZYME CORPORATION (US) | 2007-08-08 | — | — | EP | disclosed |
| US-20070021509-A1 | Phosphate transport inhibitors | JOZEFIAK THOMAS H | 2007-01-25 | — | — | US | disclosed |
| US-20070021509-A1 | Phosphate transport inhibitors | JOZEFIAK THOMAS H | 2007-01-25 | — | — | US | disclosed |
| US-20070021509-A1 | Phosphate transport inhibitors | JOZEFIAK THOMAS H | 2007-01-25 | — | — | US | disclosed |
| US-7119120-B2 | Phosphate transport inhibitors | GENZYME CORPORATION (US) | 2006-10-10 | — | — | US | disclosed |
| EP-1465638-A2 | PHOSPHATE TRANSPORT INHIBITORS | GENZYME CORPORATION (US) | 2004-10-13 | — | — | EP | disclosed |
| US-20040019113-A1 | Phosphate transport inhibitors | GELTEX PHARMACEUTICALS, INC. | 2004-01-29 | — | — | US | disclosed |
| WO-2003057225-A2 | PHOSPHATE TRANSPORT INHIBITORS | GENZYME CORPORATION (US) | 2003-07-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040019113-A1 | Phosphate transport inhibitors | SLC34A1, SLC34A2, SLC20A1 | SLC10A6 12/4885SLC10A2 81/4885SLC10A1 30/4885 |
| US-20070021509-A1 | Phosphate transport inhibitors | SLC34A2, SLC34A1, SLC20A1 | SLC10A6 10/4885SLC10A2 81/4885SLC10A1 30/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.