SCHEMBL5598119

SCHEMBL5598119

Oc1ccc(C2(c3ccc(O)cc3)C=CCCC2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 4/20 0.47
ESR1 P03372 2/20 0.47
MMP2 P08253 1/20 0.32
MMP9 P14780 1/20 0.32
KDM4E B2RXH2 1/20 0.32
MEN1 O00255 1/20 0.32
NPC1 O15118 1/20 0.32
CA12 O43570 1/20 0.32
GMNN O75496 1/20 0.32
ALDH1A1 P00352 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
LMNA P02545 1/20 0.32
CA3 P07451 1/20 0.32
CYP3A4 P08684 1/20 0.32
MAPT P10636 1/20 0.32
TYR P14679 1/20 0.32
HPGD P15428 1/20 0.32
ALOX15 P16050 1/20 0.32
NFKB1 P19838 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29418154 0.92 ESR2 (0.52) ESR2ESR1MMP2MMP9ALDH1A1
SCHEMBL3035977 0.88 ESR2 (0.45) ESR2ESR1MMP2MMP9KDM4E
SCHEMBL9104787 0.80 ALDH1A1 (0.45) KDM4EMEN1ALDH1A1LMNAMAPT
SCHEMBL27184907 0.79 DPP4 (0.36)
SCHEMBL10070882 0.76 ESR1 (0.37) ESR2ESR1
SCHEMBL11132363 0.75 ESR1 (0.56) ESR2ESR1KDM4EMEN1ALDH1A1
SCHEMBL8087895 0.74 ESR2 (0.41) ESR2ESR1MMP2MMP9CA12
SCHEMBL4803159 0.72 HPGD (0.40) MEN1NPC1LMNAMAPTHPGD
Hydroquinone SCHEMBL9340194 0.67 ALOX15 (0.53) ESR2ESR1KDM4EMEN1NPC1
SCHEMBL28146651 0.65 ESR2 (0.39) ESR2ESR1KDM4EMEN1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104203889-A Novel bis(4-hydroxyphenyl) cyclohexene HONSHU CHEMICAL IND 2014-12-10 CN disclosed
US-7169844-B2 Light resistance and chemical resistance DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2007-01-30 US disclosed
US-20060205847-A1 Lactone-added hindered amine compound CIBA SPECIALTY CHEMICALS CORP. 2006-09-14 US disclosed
US-20060155015-A1 Aqueous emulsion of ultraviolet-absorbing resin and emulsion resin composition DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2006-07-13 US disclosed
EP-1642892-A1 LACTONE-ADDED HINDERED AMINE COMPOUND Daicel Chemical Industries, Ltd. (JP) 2006-04-05 EP disclosed
EP-1637552-A1 AQUEOUS EMULSION OF ULTRAVIOLET-ABSORBING RESIN AND EMULSION RESIN COMPOSITION DAICEL CHEMICAL INDUSTRIES, Ltd. (JP) 2006-03-22 EP disclosed
US-20050121652-A1 Light resistance and chemical resistance DAICEL CHEMICAL INDUSTIRES, LTD. (JP) 2005-06-09 US disclosed
EP-1469023-A1 RESIN WITH FUNCTION OF OXIDATION INHIBITION AND EMULSION THEREOF DAICEL CHEMICAL INDUSTRIES, Ltd. (JP) 2004-10-20 EP disclosed
US-6603035-B1 A method for producing a high purity cyanate comprising reacting a phenol compound represented by the following formula SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-08-05 US disclosed
EP-0989124-B1 New polyester compounds having a benzotriazole group and a preparation method thereof DAICEL CHEM (JP) 2002-08-14 EP disclosed
EP-0989124-A1 New polyester compounds having a benzotriazole group and a preparation method thereof DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2000-03-29 EP disclosed
US-6037393-A POLYESTER OR ESTER COMPOUND WITH BENZOTRIAZOLE GROUP(S); POLYLACTONES; CHEMICAL RESISTANCE; ULTRAVIOLET RADIATION ABSORBERS DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2000-03-14 US disclosed
US-5405933-A Having units derived from aromatic dihydroxy compounds, including resorcinol and/or substituted resorcinols in defined amounts; improved flow and formability GENERAL ELECTRIC COMPANY (US) 1995-04-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060205847-A1 Lactone-added hindered amine compound H1-4, H1-0, H1-5 ESR2 1599/4885ESR1 470/4885MMP2 2799/4885
US-20060155015-A1 Aqueous emulsion of ultraviolet-absorbing resin and emulsion resin composition POLK, POLL, RARG ESR2 370/4885ESR1 327/4885MMP2 2369/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.