SCHEMBL5598219

SCHEMBL5598219

CC=Cc1cccc(C(C)CN2CCCC2)c1

nearest known ligand 0.50

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.46
KMT2A Q03164 2/20 0.46
NPC1 O15118 2/20 0.46
MEN1 O00255 1/20 0.46
ALDH1A1 P00352 1/20 0.42
GFER P55789 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
POLB P06746 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5998132 1.00 KDM4E (0.46) KDM4EKMT2ANPC1MEN1ALDH1A1
SCHEMBL29865451 1.00 KDM4E (0.46) KDM4EKMT2ANPC1MEN1ALDH1A1
SCHEMBL5598270 0.99 KDM4E (0.48) KDM4EKMT2ANPC1MEN1ALDH1A1
SCHEMBL29536930 0.84 KDM4E (0.47) KDM4EKMT2ANPC1ALDH1A1GFER
SCHEMBL21555691 0.84 KDM4E (0.47) KDM4EKMT2ANPC1ALDH1A1GFER
SCHEMBL11518269 0.77 HDAC4 (0.51) ALDH1A1SMN1; SMN2
SCHEMBL10447240 0.75 TAAR1 (0.50) SMN1; SMN2
SCHEMBL11200342 0.75 SMN1; SMN2 (0.51) KDM4EALDH1A1GFERL3MBTL1SMN1; SMN2
SCHEMBL8267685 0.74 ALDH1A1 (0.69) KDM4EKMT2ANPC1ALDH1A1GFER
SCHEMBL7792404 0.73 ALDH1A1 (0.67) KDM4EKMT2ANPC1ALDH1A1GFER

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3059259-B1 END-FUNCTIONAL CONJUGATED DIENE-BASED POLYMER AND MANUFACTURING METHOD THEREFOR LG CHEMICAL LTD (KR) 2018-02-21 EP claimed
US-20240141149-A1 Rubber Composition Containing Bio-Elastomer and Method for Preparing the Same LG CHEM, LTD. (KR) 2024-05-02 US disclosed
EP-4276147-A1 RUBBER COMPOSITION COMPRISING BIOELASTIC BODY, AND PREPARATION METHOD THEREFOR LG Chem, Ltd. (KR) 2023-11-15 EP disclosed
CN-116848185-A Rubber composition containing bioelastomer and method for producing the same 株式会社LG化学 2023-10-03 CN disclosed
CN-115066463-B Oil-extended modified conjugated diene polymer, method for preparing same, and rubber composition comprising same 株式会社LG化学 2023-06-20 CN disclosed
WO-2023085838-A1 RUBBER COMPOSITION COMPRISING BIOELASTIC BODY, AND PREPARATION METHOD THEREFOR 주식회사 엘지화학 2023-05-19 WO disclosed
CN-115066463-A Oil-extended modified conjugated diene polymer, method for producing same, and rubber composition containing same 株式会社LG化学 2022-09-16 CN disclosed
US-7222650-B2 Tire with a tread comprising a rubbery polymer of a functionalized monomer THE GOODYEAR TIRE & RUBBER COMPANY (US) 2007-05-29 US disclosed
US-7041761-B2 Functionalized monomers for synthesis of rubbery polymers THE GOODYEAR TIRE & RUBBER COMPANY (US) 2006-05-09 US disclosed
US-6995224-B2 Functionalized monomers for synthesis of rubbery polymers THE GOODYEAR TIRE & RUBBER COMPANY (US) 2006-02-07 US disclosed
US-6933358-B2 Reacting secordary amine with 2,3-dihalopropene forming monomer THE GOODYEAR TIRE & RUBBER COMPANY (US) 2005-08-23 US disclosed
US-20050131181-A1 FUNCTIONALIZED MONOMERS FOR SYNTHESIS OF RUBBERY POLYMERS THE GOODYEAR TIRE & RUBBER COMPANY 2005-06-16 US disclosed
US-6901982-B2 Functionalized monomers for synthesis of rubbery polymers THE GOODYEAR TIRE & RUBBER COMPANY (US) 2005-06-07 US disclosed
US-20050006014-A1 Functionalized monomers for synthesis of rubbery polymers THE GOODYEAR TIRE & RUBBER COMPANY 2005-01-13 US disclosed
US-20040122224-A1 Functionalized monomers for synthesis of rubbery polymers THE GOODYEAR TIRE & RUBBER COMPANY 2004-06-24 US disclosed
US-20040063884-A1 Functionalized monomers for synthesis of rubbery polymers THE GOODYEAR TIRE & RUBBER COMPANY 2004-04-01 US disclosed
US-20040048972-A1 Functionalized monomers for synthesis of rubbery polymers GOODYEAR TIRE & RUBBER COMPANY, THE 2004-03-11 US disclosed
US-20040044157-A1 Functionalized monomers for synthesis of rubbery polymers GOODYEAR TIRE & RUBBER COMPANY, THE 2004-03-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050006014-A1 Functionalized monomers for synthesis of rubbery polymers RDX, DPY30, COIL KDM4E 1828/4885KMT2A 3652/4885NPC1 4307/4885
US-20040063884-A1 Functionalized monomers for synthesis of rubbery polymers RDX, DPY30, RIF1 KDM4E 2045/4885KMT2A 2964/4885NPC1 3813/4885
US-20040122224-A1 Functionalized monomers for synthesis of rubbery polymers PRMT1, DDR2, DNMT3A KDM4E 622/4885KMT2A 187/4885NPC1 4716/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.