Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.48 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.43 |
| ▸ | CHRNG | P07510 | 1/20 | 0.43 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.43 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | CHRND | Q07001 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11141005 | 0.88 | LMNA (0.50) | SMN1; SMN2TDP1MBTD1L3MBTL3LMNA | |
| Hydrochloric Acid SCHEMBL11143620 | 0.87 | LMNA (0.49) | SMN1; SMN2TDP1MBTD1L3MBTL3LMNA | |
| SCHEMBL4060240 | 0.85 | ALDH1A1 (0.47) | SMN1; SMN2LMNAALDH1A1KDM4EGFER | |
| Hydrochloric Acid SCHEMBL11139189 | 0.83 | KMT2A (0.43) | SMN1; SMN2TDP1MBTD1L3MBTL3LMNA | |
| SCHEMBL11144985 | 0.81 | MBTD1 (0.44) | SMN1; SMN2TDP1MBTD1L3MBTL3LMNA | |
| SCHEMBL6202414 | 0.81 | SMN1; SMN2 (0.50) | SMN1; SMN2TDP1MBTD1L3MBTL3LMNA | |
| SCHEMBL7792404 | 0.80 | ALDH1A1 (0.67) | SMN1; SMN2ALDH1A1KDM4EGFERL3MBTL1 | |
| SCHEMBL27625173 | 0.79 | SMN1; SMN2 (0.43) | SMN1; SMN2TDP1MBTD1L3MBTL3LMNA | |
| SCHEMBL11187062 | 0.79 | SLC18A3 (0.44) | SMN1; SMN2MBTD1L3MBTL3LMNAALDH1A1 | |
| SCHEMBL28163310 | 0.79 | SMN1; SMN2 (0.45) | SMN1; SMN2TDP1MBTD1L3MBTL3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4417052-A | ANTIINFLAMMATORY AGENTS; ANALGESICS; VIRICIDES | STERLING DRUG INC. (US) | 1983-11-22 | — | — | US | disclosed |
| US-4308382-A | ANTIINFLAMMATORY AGENTS | STERLING DRUG INC. (US) | 1981-12-29 | — | — | US | disclosed |
| US-4216326-A | Intermediates for preparing anti-inflammatory phenyl-lower-alkylamines | STERLING DRUG INC. (US) | 1980-08-05 | — | — | US | disclosed |