Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.47 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.47 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.41 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21724320 | 0.77 | KDM4E (0.47) | CHRNB2CHRNB4CHRNA3CHRNA4KDM4E | |
| SCHEMBL29994131 | 0.77 | TSHR (0.45) | CHRNB2CHRNB4CHRNA3CHRNA4KDM4E | |
| SCHEMBL14506085 | 0.77 | ALDH1A1 (0.42) | KDM4EALDH1A1TDP1TSHRL3MBTL1 | |
| SCHEMBL1901573 | 0.77 | CHRNB2 (0.53) | CHRNB2CHRNB4CHRNA3CHRNA4KDM4E | |
| SCHEMBL2669695 | 0.75 | CYP1A2 (0.54) | KDM4EALDH1A1SMN1; SMN2TSHRL3MBTL1 | |
| SCHEMBL17549816 | 0.75 | CHRNB2 (0.67) | CHRNB2CHRNB4CHRNA3CHRNA4ALDH1A1 | |
| SCHEMBL21382113 | 0.75 | ALDH1A1 (0.47) | KDM4EALDH1A1SMN1; SMN2TDP1TSHR | |
| SCHEMBL30405344 | 0.74 | CHRNB2 (0.39) | CHRNB2CHRNB4CHRNA3CHRNA4KDM4E | |
| SCHEMBL1684467 | 0.74 | PYCR1 (0.42) | KDM4EALDH1A1SMN1; SMN2MAPTHPGD | |
| SCHEMBL1893045 | 0.73 | PYCR1 (0.52) | KDM4EALDH1A1SMN1; SMN2TSHRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1831146-A1 | HYDROXYCARBONYLATION OF ARYL AND VINYL BROMIDES | Finorga (FR) | 2007-09-12 | — | — | EP | claimed |
| WO-2006066975-A1 | HYDROXYCARBONYLATION OF ARYL AND VINYL BROMIDES | FINORGA (FR) | 2006-06-29 | — | — | WO | claimed |