Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 4/20 | 0.54 |
| ▸ | PLK1 | P53350 | 9/20 | 0.49 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.47 |
| ▸ | PTPRO | Q16827 | 1/20 | 0.47 |
| ▸ | PLK3 | Q9H4B4 | 2/20 | 0.45 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.44 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.43 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.43 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | RARA | P10276 | 1/20 | 0.43 |
| ▸ | RARG | P13631 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2858924 | 0.85 | RARB (0.61) | RARBPLK1S1PR1S1PR3S1PR2 | |
| SCHEMBL551744 | 0.80 | RARB (0.68) | RARBPLK1PLK3AGTR1AGTR2 | |
| SCHEMBL2853542 | 0.78 | CYP4A11 (0.55) | RARBPLK1PTPN11S1PR1S1PR3 | |
| SCHEMBL2851976 | 0.77 | RARB (0.52) | RARBPLK1PTPN11PTPROPPARA | |
| SCHEMBL5598223 | 0.77 | PLK1 (0.50) | RARBPLK1PTPN11PTPROPPARA | |
| SCHEMBL5598090 | 0.77 | PLK1 (0.47) | RARBPLK1PTPN11PTPROPPARA | |
| SCHEMBL2857126 | 0.76 | ESR1 (0.54) | PLK1S1PR1S1PR3S1PR2 | |
| SCHEMBL2857121 | 0.76 | S1PR1 (0.45) | PLK1S1PR1S1PR3S1PR2 | |
| SCHEMBL1811178 | 0.76 | RARB (0.73) | RARBPLK1PTPN11PTPRORARA | |
| SCHEMBL2858029 | 0.76 | FFAR1 (0.54) | NR1H4S1PR1S1PR3S1PR2PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070105913-A1 | Alkynyl aryl carboxamides | APPLIED RESEARCH SYSTEMS ARS HOLDINGS N.V. (NL) | 2007-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070105913-A1 | Alkynyl aryl carboxamides | ECHS1, IRS1, HCCS | RARB 4697/4885PLK1 4382/4885PTPN11 97/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.