Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 4/20 | 0.68 |
| ▸ | PPARA | Q07869 | 2/20 | 0.62 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.58 |
| ▸ | PPARG | P37231 | 1/20 | 0.57 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.55 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.55 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | THPO | P40225 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20503376 | 0.93 | RARB (0.78) | RARBPPARAKAT8PPARGALDH1A1 | |
| SCHEMBL4308582 | 0.93 | RARB (0.78) | RARBPPARAKAT8PPARGALDH1A1 | |
| SCHEMBL11028587 | 0.93 | RARB (0.78) | RARBPPARAKAT8PPARGALDH1A1 | |
| SCHEMBL5609669 | 0.93 | RARB (0.78) | RARBPPARAKAT8PPARGALDH1A1 | |
| SCHEMBL10476041 | 0.89 | RARB (0.59) | RARBPPARAKAT8PPARGAGTR1 | |
| SCHEMBL20556345 | 0.87 | RARB (0.89) | RARBPPARAALDH1A1MEN1MAPT | |
| SCHEMBL20503286 | 0.86 | KAT8 (0.62) | RARBPPARAKAT8PPARGSKP2 | |
| SCHEMBL21555386 | 0.86 | SKP2 (0.54) | RARBPPARAKAT8PPARGSKP2 | |
| SCHEMBL2367978 | 0.86 | RARB (0.86) | RARBPPARAALDH1A1MEN1MAPT | |
| SCHEMBL1356365 | 0.86 | KAT8 (0.66) | RARBPPARAKAT8PPARGALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115491703-B | Electrochemical synthesis method for synthesizing phthalide and derivatives thereof based on oxidative dehydrogenation | 安阳工学院 | 2025-04-18 | — | — | CN | disclosed |
| EP-3377473-B1 | MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS | RQX PHARMACEUTICALS INC (US) | 2024-06-19 | — | — | EP | disclosed |
| US-20230133817-A1 | MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS | RQX PHARMACEUTICALS INC (US) | 2023-05-04 | — | — | US | disclosed |
| US-20230133817-A1 | MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS | RQX PHARMACEUTICALS INC (US) | 2023-05-04 | — | — | US | disclosed |
| US-20230133817-A1 | MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS | RQX PHARMACEUTICALS INC (US) | 2023-05-04 | — | — | US | disclosed |
| CN-115491703-A | Electrochemical synthesis method for synthesizing phthalide and derivatives thereof based on oxidative dehydrogenation | 安阳工学院 | 2022-12-20 | — | — | CN | disclosed |
| CN-108884058-B | Macrocyclic broad spectrum antibiotics | 阿奇克斯制药公司 | 2022-04-29 | — | — | CN | disclosed |
| CN-108884058-A | MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS | 阿奇克斯制药公司 | 2018-11-23 | — | — | CN | disclosed |
| US-20180327367-A1 | MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS | WUXI APPTEC CO., LTD (CN) | 2018-11-15 | — | — | US | disclosed |
| EP-3377473-A1 | MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS | RQX Pharmaceuticals, Inc. (US) | 2018-09-26 | — | — | EP | disclosed |
| US-8110329-B2 | Charge controlling agent and toner | CANON KABUSHIKI KAISHA (JP) | 2012-02-07 | — | — | US | disclosed |
| US-20070111125-A1 | CHARGE CONTROLLING AGENT AND TONER | CANON KABUSHIKI KAISHA (JP) | 2007-05-17 | — | — | US | disclosed |
| CN-1277846-C | Organic-inorganic nanocomposite and preparation method thereof | LG CHEMICAL LTD (KR) | 2006-10-04 | — | — | CN | disclosed |
| CN-1498228-A | Organic-inorganic nanocomposite and preparation method thereof | LG��ѧ��ʽ���� | 2004-05-19 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180327367-A1 | MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS | MRPL21, PEPD, CTSC | RARB 1554/4885PPARA 3021/4885KAT8 4090/4885 |
| US-20230133817-A1 | MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS | MRPL21, PEPD, CTSC | RARB 1554/4885PPARA 3021/4885KAT8 4090/4885 |
| US-20070111125-A1 | CHARGE CONTROLLING AGENT AND TONER | CA2, ACTR2, CA12 | RARB 2051/4885PPARA 2350/4885KAT8 442/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.