Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | NQO1 | P15559 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2211390 | 0.84 | MAPK1 (0.45) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL1150521 | 0.78 | BRD4 (0.42) | HSD17B10MAPTESR2ALDH1A1MEN1 | |
| SCHEMBL5598599 | 0.74 | ALDH1A1 (0.55) | HSD17B10ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL2698875 | 0.72 | DYRK1A (0.43) | HSD17B10MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL2700901 | 0.72 | AHR (0.40) | HSD17B10ALDH1A1KDM4EGPR84 | |
| SCHEMBL413709 | 0.68 | KDR (0.54) | — | |
| SCHEMBL827340 | 0.67 | MEN1 (0.65) | HSD17B10MAPTESR2ALDH1A1MEN1 | |
| SCHEMBL7290836 | 0.67 | ALDH1A1 (0.47) | HSD17B10ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL785557 | 0.66 | L3MBTL1 (0.59) | HSD17B10MAPTESR2ALDH1A1MEN1 | |
| SCHEMBL6626983 | 0.66 | MEN1 (0.62) | HSD17B10MAPTESR2ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007113548-A1 | NAPHTHYRIDINE DERIVATIVES | ASTRAZENECA AB (SE) | 2007-10-11 | — | — | WO | disclosed |