Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.65 |
| ▸ | MAOA | P21397 | 1/20 | 0.55 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.51 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.51 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.51 |
| ▸ | CHRNA10 | Q9GZZ6 | 2/20 | 0.51 |
| ▸ | CHRNA9 | Q9UGM1 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.50 |
| ▸ | LTA4H | P09960 | 1/20 | 0.48 |
| ▸ | NQO1 | P15559 | 1/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.46 |
| ▸ | AHR | P35869 | 3/20 | 0.46 |
| ▸ | CMA1 | P23946 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6626983 | 0.98 | MEN1 (0.62) | MEN1KMT2APOLBMAPK1MAOA | |
| SCHEMBL6626981 | 0.96 | MEN1 (0.61) | MEN1KMT2APOLBMAPK1MAOA | |
| SCHEMBL30301439 | 0.87 | MEN1 (0.62) | MEN1KMT2APOLBMAPK1MAOA | |
| SCHEMBL3790084 | 0.87 | MAPK1 (0.62) | MEN1KMT2APOLBMAPK1MAOA | |
| SCHEMBL3794904 | 0.87 | MEN1 (0.62) | MEN1KMT2APOLBMAPK1MAOA | |
| SCHEMBL1196091 | 0.85 | LTA4H (0.55) | MEN1KMT2APOLBMAPK1MAOA | |
| SCHEMBL16511229 | 0.84 | APP (0.53) | MEN1KMT2APOLBMAPK1MAOA | |
| SCHEMBL10045292 | 0.82 | MEN1 (0.66) | MEN1KMT2APOLBMAPK1MAOA | |
| SCHEMBL9983791 | 0.82 | MAPK1 (0.66) | MEN1KMT2APOLBMAPK1MAOA | |
| SCHEMBL30041284 | 0.82 | MAPK1 (0.66) | MEN1KMT2APOLBMAPK1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115232052-A | Tetraindolylmethane compound and preparation method and application thereof | 南京工业大学 | 2022-10-25 | — | — | CN | claimed |
| CN-114920684-B | Selenium-containing benzamide compound and synthetic method and application thereof | 浙江工业大学 | 2023-12-05 | — | — | CN | disclosed |
| CN-114736150-B | off-DNA and on-DNA synthesis method of arylselenoindole compound | 浙江工业大学 | 2023-03-31 | — | — | CN | disclosed |
| CN-115232052-A | Tetraindolylmethane compound and preparation method and application thereof | 南京工业大学 | 2022-10-25 | — | — | CN | disclosed |
| CN-114920684-A | Selenium-containing benzamide compound and synthesis method and application thereof | 浙江工业大学 | 2022-08-19 | — | — | CN | disclosed |
| CN-114736150-A | off-DNA and on-DNA synthesis method of arylselenoindole compound | 浙江工业大学 | 2022-07-12 | — | — | CN | disclosed |
| US-20210300912-A1 | ARYL HYDROCARBON RECEPTOR (AHR) AGONISTS AND USES THEREOF | Ikena Oncology, Inc. | 2021-09-30 | — | — | US | disclosed |
| US-20210300912-A1 | ARYL HYDROCARBON RECEPTOR (AHR) AGONISTS AND USES THEREOF | Ikena Oncology, Inc. | 2021-09-30 | — | — | US | disclosed |
| WO-2021127302-A1 | 2-(1H-INDOLE-3-CARBONYL)-THIAZOLE-4-CARBOXAMIDE DERIVATIVES AND RELATED COMPOUNDS AS ARYL HYDROCARBON RECEPTOR (AHR) AGONISTS FOR THE TREATMENT OF E.G. ANGIOGENESIS IMPLICATED OR INFLAMMATORY DISORDERS | Ikena Oncology, Inc. (US) | 2021-06-24 | — | — | WO | disclosed |
| WO-2018009539-A1 | INHIBITORS OF HEXOKINASE AND METHODS OF USE THEREOF | VTV THERAPEUTICS LLC (US) | 2018-01-11 | — | — | WO | disclosed |
| US-20040048915-A1 | Methods and compounds for treating proliferative diseases | ENGLER THOMAS ALBERT (US) | 2004-03-11 | — | — | US | disclosed |
| US-20040019097-A1 | Method for producing trimer of indole derivative, and trimer of indole derivative and laminated structure thereof | MITSUBISHI CHEMICAL CORPORATION (JP) | 2004-01-29 | — | — | US | disclosed |
| US-20030207883-A1 | Indazole benzimidazole compounds | CHIRON CORPORATION | 2003-11-06 | — | — | US | disclosed |
| EP-1327632-A1 | METHOD FOR PRODUCING TRIMER OF INDOLE DERIVATIVE, AND TRIMER OF INDOLE DERIVATIVE AND LAMINATED STRUCTURE THEREOF | Mitsubishi Rayon Co., Ltd. (JP) | 2003-07-16 | — | — | EP | disclosed |
| EP-1325011-A2 | METHODS AND COMPOUNDS FOR TREATING PROLIFERATIVE DISEASES | ELI LILLY AND COMPANY (US) | 2003-07-09 | — | — | EP | disclosed |
| WO-2003004488-A1 | INDAZOLE BENZIMIDAZOLE COMPOUNDS AS TYROSINE AND SERINE/THREONINE KINASE INHIBITORS | CHIRON CORPORATION (US) | 2003-01-16 | — | — | WO | disclosed |
| EP-0274825-B1 | Indole derivatives and their uses in agriculture | SYNGENTA LTD (GB) | 2002-09-11 | — | — | EP | disclosed |
| WO-2002028861-A2 | METHODS AND COMPOUNDS FOR TREATING PROLIFERATIVE DISEASES | ELI LILLY AND COMPANY (US) | 2002-04-11 | — | — | WO | disclosed |
| US-4812162-A | PLANT GROWTH REGULATORS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-03-14 | — | — | US | disclosed |
| EP-0274825-A2 | Indole derivatives and their uses in agriculture | ZENECA LIMITED (GB) | 1988-07-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210300912-A1 | ARYL HYDROCARBON RECEPTOR (AHR) AGONISTS AND USES THEREOF | AHR, ARNT, HCAR1 | MEN1 4851/4885KMT2A 1031/4885POLB 3015/4885 |
| US-20040048915-A1 | Methods and compounds for treating proliferative diseases | CDK4, CCNI, CCNA1 | MEN1 2055/4885KMT2A 1627/4885POLB 142/4885 |
| US-20040019097-A1 | Method for producing trimer of indole derivative, and trimer of indole derivative and laminated structure thereof | IDO1, IDO2, INMT | MEN1 2605/4885KMT2A 2941/4885POLB 3660/4885 |
| US-20030207883-A1 | Indazole benzimidazole compounds | SLCO1B3, SLCO1B1, SLCO4C1 | MEN1 1653/4885KMT2A 3144/4885POLB 1795/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.