SCHEMBL5598484

SCHEMBL5598484

Cc1ccc(CC(c2ccccc2)c2ccccc2)c(C)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.46
HTT P42858 3/20 0.46
RAB9A P51151 2/20 0.46
LMNA P02545 2/20 0.46
PSMB5 P28074 2/20 0.46
PSMB8 P28062 1/20 0.46
TDP1 Q9NUW8 2/20 0.43
BRD4 O60885 1/20 0.43
NPC1 O15118 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
ALDH1A1 P00352 2/20 0.42
ALOX12 P18054 1/20 0.42
NR3C1 P04150 1/20 0.41
PGR P06401 1/20 0.41
NR3C2 P08235 1/20 0.41
TACR1 P25103 1/20 0.41
TNF P01375 1/20 0.40
KDM4E B2RXH2 1/20 0.39
ATM Q13315 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6546939 0.85 PSMB5 (0.44) SMN1; SMN2HTTRAB9ALMNAPSMB5
SCHEMBL10969479 0.79 CYP19A1 (0.47) SMN1; SMN2HTTRAB9ALMNATDP1
SCHEMBL3031236 0.75 KDM4E (0.47) SMN1; SMN2HTTRAB9ALMNAPSMB5
SCHEMBL6548345 0.75 RIPK1 (0.43) SMN1; SMN2HTTRAB9ALMNAPSMB5
SCHEMBL10893319 0.74 HTT (0.53) HTT
Hydrochloric Acid SCHEMBL5972895 0.74 RAB9A (0.44) SMN1; SMN2HTTRAB9ALMNAPSMB5
SCHEMBL3672505 0.74 SMN1; SMN2 (0.59) SMN1; SMN2HTTRAB9ALMNANPC1
SCHEMBL28517764 0.74 TDP1 (0.38) SMN1; SMN2HTTLMNATDP1BRD4
SCHEMBL3672507 0.74 SMN1; SMN2 (0.59) SMN1; SMN2HTTRAB9ALMNANPC1
SCHEMBL11437831 0.74 NR3C1 (0.44) SMN1; SMN2HTTRAB9ALMNAPSMB5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108291063-B Resin composition containing insecticidal component 创新病媒控制联合集团 2021-04-27 CN disclosed
US-20070003587-A1 Granular pesticidal formulation SUMITOMO CHEMICAL COMPANY, LIMITED 2007-01-04 US disclosed
US-6620421-B1 Excellent in disintegration in water and storage stability SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-09-16 US disclosed
US-6596292-B2 Mixture of dispersant, boron compound, smectite and water soluble carrier SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-07-22 US disclosed
EP-1166630-B1 Solid pesticidal formulation SUMITOMO CHEMICAL CO (JP) 2003-07-09 EP disclosed
US-20020019441-A1 Solid pesticidal formulation SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-02-14 US disclosed
EP-1166630-A1 Solid pesticidal formulation SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-01-02 EP disclosed
US-4999333-A For facsimile and thermal printing FUJI PHOTO FILM CO., LTD. (JP) 1991-03-12 US disclosed