Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | CA12 | O43570 | 3/20 | 0.38 |
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | CA9 | Q16790 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.37 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | PHGDH | O43175 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17934675 | 1.00 | MAPT (0.44) | MAPTSMN1; SMN2CA12CA1CA9 | |
| SCHEMBL24378109 | 0.82 | MAPT (0.39) | MAPTSMN1; SMN2CA12CA1CA9 | |
| SCHEMBL20120036 | 0.79 | MAPT (0.43) | MAPTSMN1; SMN2CA12CA1CA9 | |
| SCHEMBL5598109 | 0.78 | TGM2 (0.32) | MAPTSMN1; SMN2CA12CA1CA9 | |
| SCHEMBL13667588 | 0.78 | MAPT (0.39) | MAPTSMN1; SMN2CA12CA1CA9 | |
| SCHEMBL9251104 | 0.77 | SMN1; SMN2 (0.46) | MAPTSMN1; SMN2CA12CA1CA9 | |
| SCHEMBL9251101 | 0.77 | SMN1; SMN2 (0.46) | MAPTSMN1; SMN2CA12CA1CA9 | |
| SCHEMBL23451220 | 0.77 | SMN1; SMN2 (0.41) | MAPTSMN1; SMN2CA12CA1CA9 | |
| SCHEMBL9248623 | 0.77 | MAPT (0.41) | MAPTSMN1; SMN2CA12CA1CA9 | |
| SCHEMBL9248620 | 0.77 | MAPT (0.41) | MAPTSMN1; SMN2CA12CA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7222650-B2 | Tire with a tread comprising a rubbery polymer of a functionalized monomer | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2007-05-29 | — | — | US | disclosed |
| US-7041761-B2 | Functionalized monomers for synthesis of rubbery polymers | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2006-05-09 | — | — | US | disclosed |
| US-6995224-B2 | Functionalized monomers for synthesis of rubbery polymers | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2006-02-07 | — | — | US | disclosed |
| US-6936669-B2 | Functionalized monomers for synthesis of rubbery polymers | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2005-08-30 | — | — | US | disclosed |
| US-6933358-B2 | Reacting secordary amine with 2,3-dihalopropene forming monomer | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2005-08-23 | — | — | US | disclosed |
| US-20050131181-A1 | FUNCTIONALIZED MONOMERS FOR SYNTHESIS OF RUBBERY POLYMERS | THE GOODYEAR TIRE & RUBBER COMPANY | 2005-06-16 | — | — | US | disclosed |
| US-6901982-B2 | Functionalized monomers for synthesis of rubbery polymers | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2005-06-07 | — | — | US | disclosed |
| US-20050049377-A1 | Functionalized monomers for synthesis of rubbery polymers | THE GOODYEAR TIRE & RUBBER COMPANY | 2005-03-03 | — | — | US | disclosed |
| US-20050006014-A1 | Functionalized monomers for synthesis of rubbery polymers | THE GOODYEAR TIRE & RUBBER COMPANY | 2005-01-13 | — | — | US | disclosed |
| US-6825306-B2 | ADDITION COPOLYMERIZATION OF CONJUGATED DIENE AND STYRENE MONOMER FUNCTIONALIZED WITH SILYL(OXY)ALKYL GROUP; TIRES, HOSES; ANIONIC POLYMERIZATION | THE GOODYEAR TIRE & RUBBER COMPANY | 2004-11-30 | — | — | US | disclosed |
| US-6812307-B2 | FORMING FILLER COMPATIBLE MATERIALS; SOLUTION COPOLYMERIZING AT LEAST CONJUGATED DIOLEFIN AND AMINE FUNCTIONALIZED STYRENE MONOMER | THE GOODYEAR TIRE & RUBBER COMPANY | 2004-11-02 | — | — | US | disclosed |
| US-20040122224-A1 | Functionalized monomers for synthesis of rubbery polymers | THE GOODYEAR TIRE & RUBBER COMPANY | 2004-06-24 | — | — | US | disclosed |
| US-20040122194-A1 | Functionalized monomers for synthesis of rubbery polymers | THE GOODYEAR TIRE & RUBBER COMPANY | 2004-06-24 | — | — | US | disclosed |
| US-6753447-B2 | REACTING SECONDARY AMINE WITH 2,3- DIHALOPROPENE TO PRODUCE A VINYL HALIDE CONTAINING CYCLIC TERTIARY AMINE; REACTING WITH VINYL MAGNESIUM HALIDE IN POLAR SOLVENT | THE GOODYEAR TIRE & RUBBER COMPANY | 2004-06-22 | — | — | US | disclosed |
| US-20040116635-A1 | Functionalized monomers for synthesis of rubbery polymers | GOODYEAR TIRE & RUBBER COMPANY, THE | 2004-06-17 | — | — | US | disclosed |
| US-20040063884-A1 | Functionalized monomers for synthesis of rubbery polymers | THE GOODYEAR TIRE & RUBBER COMPANY | 2004-04-01 | — | — | US | disclosed |
| US-20040048972-A1 | Functionalized monomers for synthesis of rubbery polymers | GOODYEAR TIRE & RUBBER COMPANY, THE | 2004-03-11 | — | — | US | disclosed |
| US-20040044157-A1 | Functionalized monomers for synthesis of rubbery polymers | GOODYEAR TIRE & RUBBER COMPANY, THE | 2004-03-04 | — | — | US | disclosed |
| US-20040044202-A1 | Functionalized monomers for synthesis of rubbery polymers | THE GOODYEAR TIRE & RUBBER COMPANY | 2004-03-04 | — | — | US | disclosed |
| US-6693160-B1 | FREE RADICAL COPOLYMERS OF CONJUGATED DIOLEFIN AND NITROGEN HETEROCYCLE FUNCTIONALIZED MONOMERS; LOW HYSTERESIS; FILLER COMPATIBILITY | THE GOODYEAR TIRE & RUBBER COMPANY | 2004-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040044202-A1 | Functionalized monomers for synthesis of rubbery polymers | PRMT1, DDR2, DNMT3A | MAPT 3807/4885SMN1; SMN2 2459/4885CA12 3464/4885 |
| US-20050006014-A1 | Functionalized monomers for synthesis of rubbery polymers | RDX, DPY30, COIL | MAPT 3030/4885SMN1; SMN2 3366/4885CA12 4026/4885 |
| US-20040063884-A1 | Functionalized monomers for synthesis of rubbery polymers | RDX, DPY30, RIF1 | MAPT 3296/4885SMN1; SMN2 2557/4885CA12 4208/4885 |
| US-20040122224-A1 | Functionalized monomers for synthesis of rubbery polymers | PRMT1, DDR2, DNMT3A | MAPT 3807/4885SMN1; SMN2 2459/4885CA12 3464/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.