Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5598157 | 0.97 | ALDH1A1 (0.35) | TGM2ATMALDH1A1MAPTHPGD | |
| SCHEMBL24399598 | 0.80 | CYP1A2 (0.41) | ALDH1A1CYP1A2CA12CA1CA2 | |
| SCHEMBL5598654 | 0.78 | MAPT (0.44) | ALDH1A1MAPTTP53CA12CA1 | |
| SCHEMBL17934675 | 0.78 | MAPT (0.44) | ALDH1A1MAPTTP53CA12CA1 | |
| SCHEMBL20197148 | 0.78 | MGLL (0.31) | ALDH1A1 | |
| SCHEMBL20663345 | 0.78 | — | — | |
| SCHEMBL19577991 | 0.77 | TSHR (0.30) | — | |
| SCHEMBL23515318 | 0.74 | JAK1 (0.30) | — | |
| SCHEMBL12408140 | 0.74 | ATM (0.37) | ATMALDH1A1MAPTHPGDKDM4E | |
| SCHEMBL21163723 | 0.72 | ATM (0.31) | ATMALDH1A1MAPTHPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7222650-B2 | Tire with a tread comprising a rubbery polymer of a functionalized monomer | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2007-05-29 | — | — | US | disclosed |
| US-7041761-B2 | Functionalized monomers for synthesis of rubbery polymers | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2006-05-09 | — | — | US | disclosed |
| US-6995224-B2 | Functionalized monomers for synthesis of rubbery polymers | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2006-02-07 | — | — | US | disclosed |
| US-6936669-B2 | Functionalized monomers for synthesis of rubbery polymers | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2005-08-30 | — | — | US | disclosed |
| US-6933358-B2 | Reacting secordary amine with 2,3-dihalopropene forming monomer | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2005-08-23 | — | — | US | disclosed |
| US-20050131181-A1 | FUNCTIONALIZED MONOMERS FOR SYNTHESIS OF RUBBERY POLYMERS | THE GOODYEAR TIRE & RUBBER COMPANY | 2005-06-16 | — | — | US | disclosed |
| US-6901982-B2 | Functionalized monomers for synthesis of rubbery polymers | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2005-06-07 | — | — | US | disclosed |
| US-20050049377-A1 | Functionalized monomers for synthesis of rubbery polymers | THE GOODYEAR TIRE & RUBBER COMPANY | 2005-03-03 | — | — | US | disclosed |
| US-20050006014-A1 | Functionalized monomers for synthesis of rubbery polymers | THE GOODYEAR TIRE & RUBBER COMPANY | 2005-01-13 | — | — | US | disclosed |
| US-6825306-B2 | ADDITION COPOLYMERIZATION OF CONJUGATED DIENE AND STYRENE MONOMER FUNCTIONALIZED WITH SILYL(OXY)ALKYL GROUP; TIRES, HOSES; ANIONIC POLYMERIZATION | THE GOODYEAR TIRE & RUBBER COMPANY | 2004-11-30 | — | — | US | disclosed |
| US-6812307-B2 | FORMING FILLER COMPATIBLE MATERIALS; SOLUTION COPOLYMERIZING AT LEAST CONJUGATED DIOLEFIN AND AMINE FUNCTIONALIZED STYRENE MONOMER | THE GOODYEAR TIRE & RUBBER COMPANY | 2004-11-02 | — | — | US | disclosed |
| US-20040122194-A1 | Functionalized monomers for synthesis of rubbery polymers | THE GOODYEAR TIRE & RUBBER COMPANY | 2004-06-24 | — | — | US | disclosed |
| US-20040122224-A1 | Functionalized monomers for synthesis of rubbery polymers | THE GOODYEAR TIRE & RUBBER COMPANY | 2004-06-24 | — | — | US | disclosed |
| US-6753447-B2 | REACTING SECONDARY AMINE WITH 2,3- DIHALOPROPENE TO PRODUCE A VINYL HALIDE CONTAINING CYCLIC TERTIARY AMINE; REACTING WITH VINYL MAGNESIUM HALIDE IN POLAR SOLVENT | THE GOODYEAR TIRE & RUBBER COMPANY | 2004-06-22 | — | — | US | disclosed |
| US-20040116635-A1 | Functionalized monomers for synthesis of rubbery polymers | GOODYEAR TIRE & RUBBER COMPANY, THE | 2004-06-17 | — | — | US | disclosed |
| US-20040063884-A1 | Functionalized monomers for synthesis of rubbery polymers | THE GOODYEAR TIRE & RUBBER COMPANY | 2004-04-01 | — | — | US | disclosed |
| US-20040048972-A1 | Functionalized monomers for synthesis of rubbery polymers | GOODYEAR TIRE & RUBBER COMPANY, THE | 2004-03-11 | — | — | US | disclosed |
| US-20040044157-A1 | Functionalized monomers for synthesis of rubbery polymers | GOODYEAR TIRE & RUBBER COMPANY, THE | 2004-03-04 | — | — | US | disclosed |
| US-20040044202-A1 | Functionalized monomers for synthesis of rubbery polymers | THE GOODYEAR TIRE & RUBBER COMPANY | 2004-03-04 | — | — | US | disclosed |
| US-6693160-B1 | FREE RADICAL COPOLYMERS OF CONJUGATED DIOLEFIN AND NITROGEN HETEROCYCLE FUNCTIONALIZED MONOMERS; LOW HYSTERESIS; FILLER COMPATIBILITY | THE GOODYEAR TIRE & RUBBER COMPANY | 2004-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040044202-A1 | Functionalized monomers for synthesis of rubbery polymers | PRMT1, DDR2, DNMT3A | TGM2 2214/4885ATM 1174/4885ALDH1A1 885/4885 |
| US-20050006014-A1 | Functionalized monomers for synthesis of rubbery polymers | RDX, DPY30, COIL | TGM2 3039/4885ATM 2701/4885ALDH1A1 1516/4885 |
| US-20040063884-A1 | Functionalized monomers for synthesis of rubbery polymers | RDX, DPY30, RIF1 | TGM2 2738/4885ATM 2582/4885ALDH1A1 1009/4885 |
| US-20040122224-A1 | Functionalized monomers for synthesis of rubbery polymers | PRMT1, DDR2, DNMT3A | TGM2 2214/4885ATM 1174/4885ALDH1A1 885/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.