Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9251104 | 1.00 | SMN1; SMN2 (0.46) | SMN1; SMN2CA12CA1CA9MEN1 | |
| SCHEMBL21504070 | 0.79 | TSHR (0.43) | SMN1; SMN2CA12CA1CA9TSHR | |
| SCHEMBL12408140 | 0.78 | ATM (0.37) | SMN1; SMN2CA12CA1CA9MEN1 | |
| SCHEMBL17934675 | 0.77 | MAPT (0.44) | SMN1; SMN2CA12CA1CA9MEN1 | |
| SCHEMBL5598654 | 0.77 | MAPT (0.44) | SMN1; SMN2CA12CA1CA9MEN1 | |
| SCHEMBL23451220 | 0.77 | SMN1; SMN2 (0.41) | SMN1; SMN2CA12CA1CA9MEN1 | |
| SCHEMBL12407887 | 0.76 | ALDH1A1 (0.40) | SMN1; SMN2CA12CA1CA9MEN1 | |
| SCHEMBL12408151 | 0.76 | ALDH1A1 (0.40) | SMN1; SMN2CA12CA1CA9MEN1 | |
| SCHEMBL1896875 | 0.71 | RAB9A (0.52) | SMN1; SMN2CA12CA1CA9MEN1 | |
| SCHEMBL16116792 | 0.71 | SMN1; SMN2 (0.41) | SMN1; SMN2CA12CA1CA9MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0428460-B1 | Dienoxysilanes, methods for their preparation and alpha-ethylenic alpha-halo-aldehydes accessible therefrom | UNIV ROUEN (FR) | 1995-03-29 | — | — | EP | disclosed |
| US-5113007-A | DIENOXYSILANES | UNIVERSITE DE ROUEN (FR) | 1992-05-12 | — | — | US | disclosed |
| EP-0432068-A1 | Process for the preparation of alpha-ethylene alpha-aminoaldehydes and compounds produced therefrom | UNIVERSITE DE ROUEN (FR) | 1991-06-12 | — | — | EP | disclosed |
| EP-0428460-A1 | Dienoxysilanes, methods for their preparation and alpha-ethylenic alpha-halo-aldehydes accessible therefrom | UNIVERSITE DE ROUEN (FR) | 1991-05-22 | — | — | EP | disclosed |