Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 4/20 | 0.62 |
| ▸ | PDGFRB | P09619 | 4/20 | 0.62 |
| ▸ | KDR | P35968 | 3/20 | 0.62 |
| ▸ | MET | P08581 | 1/20 | 0.51 |
| ▸ | GSK3B | P49841 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | FLT3 | P36888 | 2/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2174210 | 0.83 | PDGFRB (0.63) | CSF1RPDGFRBKDRL3MBTL1MEN1 | |
| SCHEMBL4655471 | 0.80 | MET (0.49) | CSF1RPDGFRBKDRMETL3MBTL1 | |
| SCHEMBL2175521 | 0.80 | PDGFRB (0.63) | CSF1RPDGFRBKDRMETL3MBTL1 | |
| SCHEMBL2173579 | 0.77 | L3MBTL1 (0.58) | L3MBTL1FFAR1ALDH1A1TDP1 | |
| SCHEMBL1097150 | 0.76 | L3MBTL1 (0.61) | L3MBTL1FFAR1TDP1 | |
| SCHEMBL2175292 | 0.76 | PDGFRB (0.63) | CSF1RPDGFRBKDRMETL3MBTL1 | |
| SCHEMBL3716437 | 0.76 | TAS1R3 (0.53) | L3MBTL1MEN1KMT2AFFAR1NPC1 | |
| SCHEMBL2175002 | 0.75 | PDGFRB (0.51) | CSF1RPDGFRBKDRMETL3MBTL1 | |
| SCHEMBL1097529 | 0.74 | FLT3 (0.53) | CSF1RPDGFRBMETL3MBTL1MEN1 | |
| SCHEMBL2173825 | 0.74 | PDGFRB (0.64) | CSF1RPDGFRBKDRFLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007113548-A1 | NAPHTHYRIDINE DERIVATIVES | ASTRAZENECA AB (SE) | 2007-10-11 | — | — | WO | disclosed |