SCHEMBL5599036

SCHEMBL5599036

NOc1c(CC2CO2)cccc1OCC1CO1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.50
GLA P06280 1/20 0.50
TP53 P04637 3/20 0.45
TSHR P16473 3/20 0.45
HIF1A Q16665 2/20 0.45
CYP3A4 P08684 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
TDP1 Q9NUW8 1/20 0.42
PKM P14618 3/20 0.35
MAPT P10636 2/20 0.35
HPGD P15428 2/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
CYP1A2 P05177 1/20 0.35
PPARG P37231 1/20 0.35
LMNA P02545 1/20 0.35
GAA P10253 1/20 0.35
DRD4 P21917 1/20 0.33
SLC6A2 P23975 2/20 0.33
HTR2A P28223 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL283604 0.82 ALDH1A1 (0.55) ALDH1A1GLATP53TSHRHIF1A
SCHEMBL14397632 0.82 ALDH1A1 (0.55) ALDH1A1GLATP53TSHRHIF1A
SCHEMBL28168533 0.82 ALDH1A1 (0.53) ALDH1A1GLATP53TSHRHIF1A
SCHEMBL1129712 0.81 ALDH1A1 (0.64) ALDH1A1GLATP53TSHRHIF1A
SCHEMBL19859435 0.80 ALDH1A1 (0.54) ALDH1A1GLATP53TSHRHIF1A
SCHEMBL680532 0.79 ALDH1A1 (0.65) ALDH1A1GLATP53TSHRHIF1A
Ammonia Solution, Strong SCHEMBL10520162 0.79 ALDH1A1 (0.53) ALDH1A1GLATP53TSHRHIF1A
SCHEMBL10695774 0.78 ALDH1A1 (0.56) ALDH1A1GLATP53TSHRHIF1A
SCHEMBL729501 0.76 ALDH1A1 (0.65) ALDH1A1GLATP53TSHRHIF1A
SCHEMBL29168006 0.75 ALDH1A1 (0.56) ALDH1A1GLATP53TSHRHIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070135607-A1 TDI prepolymers with improved processing characteristics ROSTHAUSER JAMES W 2007-06-14 US disclosed
US-7030274-B2 Process for the production of carbodiimide modified organic isocyanates BAYER MATERIALSCIENCE LLC (US) 2006-04-18 US disclosed
US-20050282989-A1 TDI prepolymers with improved processing characteristics BAYER MATERIALSCIENCE LLC 2005-12-22 US disclosed
US-20050282993-A1 Process for the production of carbodiimide modified organic isocyanates COVESTRO LLC 2005-12-22 US disclosed
EP-1607425-A1 Process for the production of carboiimide modified organic isocyanates Bayer MaterialScience LLC (US) 2005-12-21 EP disclosed
US-6528609-B1 Reacting polymethylene polyphenylisocyanate with epoxide along with alcohol, converted to allophanate upon addition of a metal divalent catalyst; storage stability; mild conditions and low catalyst levels BAYER CORPORATION 2003-03-04 US disclosed
US-5837794-A REACTION OF DIAMINE WITH PHOSGENE TO FORM TOLUENE DIISOCYANATE THEN REACTION WITH ALCOHOL TO FORM URETHANE OR POLYURETHANE BAYER CORPORATION (US) 1998-11-17 US disclosed
EP-0844276-A1 Reactivity stabilization of polymethylene poly(phenylisocyanates) Bayer Corporation (US) 1998-05-27 EP disclosed
US-5726240-A MIXTURE WITH EPOXIDIZED GLYCERIDES AND/OR DIMER AND/OR TRIMER FATTY ACIDS; DISCOLORATION INHIBITION BAYER CORPORATION (US) 1998-03-10 US disclosed
EP-0631532-B1 THERMOSETTING BINDER FOR AN ABRASIVE ARTICLE MINNESOTA MINING & MFG (US) 1996-05-22 EP disclosed
US-5451446-A Polyepoxides MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-09-19 US disclosed
EP-0631532-A1 THERMOSETTING BINDER FOR AN ABRASIVE ARTICLE. MINNESOTA MINING & MFG (US) 1995-01-04 EP disclosed
WO-1993017832-A1 THERMOSETTING BINDER FOR AN ABRASIVE ARTICLE MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-09-16 WO disclosed