Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CBLB | Q13191 | 5/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | FDPS | P14324 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6650689 | 0.83 | L3MBTL1 (0.40) | OPRK1KDM4EKMT2AMEN1MAPT | |
| SCHEMBL6650490 | 0.80 | MEN1 (0.37) | OPRK1KDM4EKMT2AMEN1MAPT | |
| SCHEMBL6649435 | 0.78 | OPRK1 (0.37) | OPRK1KDM4EKMT2AMEN1POLB | |
| SCHEMBL20204951 | 0.77 | CYP11B1 (0.45) | OPRK1KMT2AMEN1MAPTPOLB | |
| SCHEMBL6651103 | 0.76 | OPRK1 (0.36) | OPRK1KDM4EKMT2AMEN1MAPT | |
| SCHEMBL25183645 | 0.76 | CYP11B1 (0.44) | OPRK1KMT2AMEN1MAPTPOLB | |
| SCHEMBL30374060 | 0.76 | CYP11B1 (0.44) | OPRK1KMT2AMEN1MAPTPOLB | |
| SCHEMBL1044189 | 0.74 | KMT2A (0.54) | KDM4EKMT2AMEN1MAPTFDPS | |
| SCHEMBL6651257 | 0.73 | KMT2A (0.44) | OPRK1KDM4EKMT2AMEN1MAPT | |
| Hydrochloric Acid SCHEMBL1875423 | 0.73 | KMT2A (0.53) | KDM4EKMT2AMEN1MAPTFDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1103243-B1 | UTILIZATION OF ARYL(OR HETEROARYL)AZOLYLCARBINOL DERIVATIVES FOR THE TREATMENT OF TROUBLES MEDIATED BY AN EXCESS OF SUBSTANCE P | ESTEVE LABOR DR (ES) | 2004-01-07 | — | — | EP | claimed |
| EP-1755678-A2 | ACTIVE SUBSTANCE COMBINATION OF A CARBINOL COMPOUND AND AN OPIOID | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2007-02-28 | — | — | EP | disclosed |
| WO-2005097192-A2 | ACTIVE SUBSTANCE COMBINATION OF A CARBINOL COMPOUND AND AN OPIOID | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2005-10-20 | — | — | WO | disclosed |