Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | FDPS | P14324 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | USP1 | O94782 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6650689 | 0.81 | L3MBTL1 (0.40) | MEN1KMT2AOPRK1FDPSL3MBTL1 | |
| SCHEMBL5599146 | 0.80 | OPRK1 (0.46) | MEN1KMT2AOPRK1FDPSL3MBTL1 | |
| SCHEMBL6651257 | 0.77 | KMT2A (0.44) | MEN1KMT2AOPRK1FDPSL3MBTL1 | |
| SCHEMBL6672328 | 0.74 | TRPM5 (0.32) | MEN1KMT2A | |
| SCHEMBL6650132 | 0.73 | HRH3 (0.33) | MEN1KMT2AKDM4E | |
| SCHEMBL6650409 | 0.72 | L3MBTL1 (0.40) | MEN1KMT2AOPRK1FDPSL3MBTL1 | |
| SCHEMBL21721828 | 0.70 | HTR1D (0.43) | MEN1KMT2AOPRK1FDPSL3MBTL1 | |
| SCHEMBL1008065 | 0.70 | CA2 (0.56) | MEN1KMT2AKDM4EMAPTTSHR | |
| SCHEMBL5601022 | 0.69 | LMNA (0.36) | MEN1KMT2AOPRK1MAPTTSHR | |
| SCHEMBL20204951 | 0.69 | CYP11B1 (0.45) | MEN1KMT2AOPRK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1103243-B1 | UTILIZATION OF ARYL(OR HETEROARYL)AZOLYLCARBINOL DERIVATIVES FOR THE TREATMENT OF TROUBLES MEDIATED BY AN EXCESS OF SUBSTANCE P | ESTEVE LABOR DR (ES) | 2004-01-07 | — | — | EP | claimed |