Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MPO | P05164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.43 |
| ▸ | MMP3 | P08254 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.40 |
| ▸ | LIG1 | P18858 | 1/20 | 0.40 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11795899 | 0.85 | GAA (0.57) | GAAKDM4EMPOSMN1; SMN2HIF1A | |
| SCHEMBL6645824 | 0.85 | GAA (0.47) | GAALMNACAPN1 | |
| SCHEMBL7664513 | 0.82 | ALDH1A1 (0.53) | KDM4ESMN1; SMN2LMNAHSD17B10 | |
| SCHEMBL7670365 | 0.82 | CAPN1 (0.34) | KDM4ELMNALIG1CAPN1HSD17B10 | |
| SCHEMBL7662720 | 0.82 | CAPN1 (0.34) | KDM4ESMN1; SMN2HDAC8LMNAHDAC1 | |
| SCHEMBL7664107 | 0.81 | KEAP1 (0.47) | GAAKDM4ESMN1; SMN2HIF1ACAPN1 | |
| SCHEMBL7661318 | 0.81 | CAPN1 (0.36) | KDM4ECAPN1CA1CA9HSD17B10 | |
| SCHEMBL7661570 | 0.81 | HTT (0.38) | GAAKDM4ECAPN1BACE1 | |
| SCHEMBL6958820 | 0.81 | ALDH1A1 (0.43) | KDM4ESMN1; SMN2LMNACAPN1 | |
| SCHEMBL6974613 | 0.81 | L3MBTL1 (0.43) | CA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107410317-A | Improve the diffusible wet tissue composition in wet tissue fabric and the wet tissue containing said composition | 明进新科技股份有限公司 | 2017-12-01 | — | — | CN | claimed |
| US-20110288168-A1 | HISTONE DEACETYLASE INHIBITORS | ERRANT GENE THERAPEUTICS, LLC | 2011-11-24 | — | — | US | claimed |
| WO-2008011074-A2 | HISTONE DEACETYLASE INHIBITORS | ERRANT GENE THERAPEUTICS, LLC (US) | 2008-01-24 | — | — | WO | claimed |
| US-7312247-B2 | Histone deacetylase inhibitors | ERRANT GENE THERAPEUTICS, LLC (US) | 2007-12-25 | — | — | US | claimed |
| US-20070037869-A1 | Treating spinal muscular atrophy with an effective amount of carboxylic acid derivative or hydroxamic acid derivative compound; treating cancer, blood disorders, genetic related metabolic disorders; 5-phenyl-2,4-pentadienoic acid | ERRANT GENE THERAPEUTICS, LLC | 2007-02-15 | — | — | US | claimed |
| EP-1408946-A4 | HISTONE DEACETYLASE INHIBITORS | CIRCAGEN PHARMACEUTICAL (US) | 2004-06-09 | — | — | EP | claimed |
| EP-1408946-A2 | HISTONE DEACETYLASE INHIBITORS | Circagen Pharmaceutical (US) | 2004-04-21 | — | — | EP | claimed |
| US-20020143052-A1 | Histone deacetylase inhibitors | ANGELA CHEN SABELLA | 2002-10-03 | — | — | US | claimed |
| WO-2002076941-A2 | HISTONE DEACETYLASE INHIBITORS | CIRCAGEN PHARMACEUTICAL (US) | 2002-10-03 | — | — | WO | claimed |
| CN-116617213-A | Cinnamoyl mycoins and their use in the treatment of bacterial infections | 西安世颂科技有限公司 | 2023-08-22 | — | — | CN | disclosed |
| CN-107410317-A | Improve the diffusible wet tissue composition in wet tissue fabric and the wet tissue containing said composition | 明进新科技股份有限公司 | 2017-12-01 | — | — | CN | disclosed |
| US-8420698-B2 | Histone deacetylase inhibitors | ERRANT GENE THERAPEUTICS, LLC (US) | 2013-04-16 | — | — | US | disclosed |
| US-8262634-B1 | Absorbent article having barrier sheet against the migration of the skin care composition | THE PROCTER & GAMBLE COMPANY (US) | 2012-09-11 | — | — | US | disclosed |
| US-20120035257-A1 | Histone Deacetylase Inhibitors | ERRANT GENE THERAPEUTICS, LLC | 2012-02-09 | — | — | US | disclosed |
| WO-2000069482-A1 | ABSORBENT ARTICLE WITH SKIN CARE COMPOSITION | THE PROCTER & GAMBLE COMPANY (US) | 2000-11-23 | — | — | WO | disclosed |
| WO-2000069481-A1 | ABSORBENT ARTICLE WITH SKIN CARE COMPOSITION | THE PROCTER & GAMBLE COMPANY (US) | 2000-11-23 | — | — | WO | disclosed |
| WO-2000069483-A1 | ABSORBENT ARTICLE WITH SKIN CARE COMPOSITION | THE PROCTER & GAMBLE COMPANY (US) | 2000-11-23 | — | — | WO | disclosed |
| WO-2000069484-A1 | ABSORBENT ARTICLE WITH SKIN CARE COMPOSITION | THE PROCTER & GAMBLE COMPANY (US) | 2000-11-23 | — | — | WO | disclosed |
| WO-2000069485-A1 | ABSORBENT ARTICLE WITH SKIN CARE COMPOSITION | THE PROCTER & GAMBLE COMPANY (US) | 2000-11-23 | — | — | WO | disclosed |
| WO-1999045973-A1 | DISPOSABLE ABSORBENT ARTICLE HAVING A SKIN CARE COMPOSITION CONTAINING AN ENZYME INHIBITOR | THE PROCTER & GAMBLE COMPANY (US) | 1999-09-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120035257-A1 | Histone Deacetylase Inhibitors | HDAC1, HDAC11, HDAC9 | GAA 130/4885KDM4E 1526/4885MPO 2299/4885 |
| US-20020143052-A1 | Histone deacetylase inhibitors | HDAC1, HDAC11, HDAC9 | GAA 127/4885KDM4E 1581/4885MPO 2172/4885 |
| US-20110288168-A1 | HISTONE DEACETYLASE INHIBITORS | HDAC1, HDAC6, HDAC5 | GAA 83/4885KDM4E 1872/4885MPO 3013/4885 |
| US-20070037869-A1 | Treating spinal muscular atrophy with an effective amount of carboxylic acid derivative or hydroxamic acid derivative compound; treating cancer, blood disorders, genetic related metabolic disorders; 5-phenyl-2,4-pentadienoic acid | HDAC5, HDAC1, ZNF277 | GAA 140/4885KDM4E 2444/4885MPO 4091/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.