Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5599937 | 0.90 | CHRNB2 (0.35) | LMNAHTTSMN1; SMN2PDE4BL3MBTL1 | |
| SCHEMBL5599549 | 0.71 | L3MBTL1 (0.42) | LMNAL3MBTL1KMT2AMAPTCHRNB2 | |
| SCHEMBL25706790 | 0.66 | KDM4E (0.45) | LMNAL3MBTL1MAPT | |
| SCHEMBL25706789 | 0.66 | MBTD1 (0.43) | KMT2AMAPT | |
| SCHEMBL25706788 | 0.66 | MBTD1 (0.43) | KMT2AMAPT | |
| SCHEMBL25706791 | 0.66 | KDM4E (0.45) | LMNAL3MBTL1MAPT | |
| SCHEMBL5611109 | 0.64 | UTS2R (0.34) | L3MBTL1 | |
| SCHEMBL5616045 | 0.62 | KDM4E (0.35) | LMNAL3MBTL1MAPT | |
| SCHEMBL15568608 | 0.60 | KDM4E (0.51) | MAPT | |
| SCHEMBL27735033 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1755678-A2 | ACTIVE SUBSTANCE COMBINATION OF A CARBINOL COMPOUND AND AN OPIOID | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2007-02-28 | — | — | EP | claimed |
| WO-2005097192-A2 | ACTIVE SUBSTANCE COMBINATION OF A CARBINOL COMPOUND AND AN OPIOID | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2005-10-20 | — | — | WO | claimed |