Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 1/20 | 0.32 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4468810 | 0.82 | CFTR (0.33) | CFTRGOPCCYP19A1 | |
| SCHEMBL5595914 | 0.82 | CFTR (0.33) | CFTRGOPCCYP19A1 | |
| SCHEMBL3967802 | 0.82 | CFTR (0.33) | CFTRGOPCCYP19A1 | |
| Lithium SCHEMBL5574358 | 0.81 | CFTR (0.32) | CFTRGOPCCYP19A1 | |
| SCHEMBL6900071 | 0.70 | — | — | |
| Hydrochloric Acid SCHEMBL4328557 | 0.70 | GPBAR1 (0.31) | — | |
| SCHEMBL21416522 | 0.70 | CFTR (0.34) | CFTRGOPCCYP19A1 | |
| Lithium SCHEMBL3971083 | 0.70 | — | — | |
| SCHEMBL5545795 | 0.69 | CFTR (0.44) | CFTRGOPC | |
| SCHEMBL13645456 | 0.63 | CYP19A1 (0.32) | CFTRGOPCCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3438183-B1 | POLYETHYLENE AND MOLDED BODY THEREOF | JAPAN POLYETHYLENE CORP (JP) | 2023-11-22 | — | — | EP | disclosed |
| CN-108884282-B | Polyethylene and molded article thereof | 日本聚乙烯株式会社 | 2021-06-08 | — | — | CN | disclosed |
| CN-107428863-B | Polyethylene for pipe and joint, and molded body thereof | 日本聚乙烯株式会社 | 2020-03-06 | — | — | CN | disclosed |
| US-10377886-B2 | Polyethylene for pipe and joint, and molded body thereof | JAPAN POLYETHYLENE CORPORATION (JP) | 2019-08-13 | — | — | US | disclosed |
| US-20190136021-A1 | POLYETHYLENE AND MOLDED BODY THEREOF | JAPAN POLYETHYLENE CORPORATION (JP) | 2019-05-09 | — | — | US | disclosed |
| EP-3438183-A1 | POLYETHYLENE AND MOLDED BODY OF SAME | Japan Polypropylene Corporation (JP) | 2019-02-06 | — | — | EP | disclosed |
| US-20180112070-A1 | POLYETHYLENE FOR PIPE AND JOINT, AND MOLDED BODY THEREOF | JAPAN POLYETHYLENE CORPORATION (JP) | 2018-04-26 | — | — | US | disclosed |
| EP-1160261-B1 | Olefin polymerization catalyst and method for polymerizing olefin using the same | JAPAN POLYCHEM CORP (JP) | 2007-06-27 | — | — | EP | disclosed |
| US-6531552-B2 | Coordination catalyst on silicate support | JAPAN POLYCHEM CORPORATION (JP) | 2003-03-11 | — | — | US | disclosed |
| US-20020004447-A1 | Olefin polymerization catalyst and method for polymerizing olefin using the same | JAPAN POLYCHEM CORPORATION (JP) | 2002-01-10 | — | — | US | disclosed |
| EP-1160261-A1 | Olefin polymerization catalyst and method for polymerizing olefin using the same | Japan Polychem Corporation (JP) | 2001-12-05 | — | — | EP | disclosed |