Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 8/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.38 |
| ▸ | LDHA | P00338 | 1/20 | 0.37 |
| ▸ | LDHB | P07195 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5599142 | 0.84 | FFAR1 (0.52) | KDM4EL3MBTL1MAPTFFAR1KMT2A | |
| SCHEMBL5600881 | 0.82 | FFAR1 (0.53) | KDM4EL3MBTL1MAPTFFAR1CYP2D6 | |
| SCHEMBL4899087 | 0.80 | KDM4E (0.71) | KDM4EL3MBTL1MAPTCYP19A1KMT2A | |
| SCHEMBL5599443 | 0.78 | KDM4E (0.46) | KDM4EL3MBTL1MAPTFFAR1CYP2D6 | |
| SCHEMBL1396167 | 0.76 | KDM4E (0.45) | KDM4EL3MBTL1MAPTFFAR1CYP19A1 | |
| SCHEMBL10611537 | 0.73 | SLC1A2 (0.44) | CYP19A1KMT2A | |
| SCHEMBL11670360 | 0.72 | L3MBTL1 (0.67) | KDM4EL3MBTL1MAPTFFAR1KMT2A | |
| SCHEMBL6980610 | 0.72 | TRPA1 (0.43) | CYP19A1 | |
| SCHEMBL5599264 | 0.71 | KDM4E (0.41) | KDM4EL3MBTL1MAPTFFAR1KMT2A | |
| SCHEMBL1503496 | 0.71 | KDM4E (0.63) | KDM4EL3MBTL1MAPTFFAR1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1746986-A1 | ACTIVE SUBSTANCE COMBINATION COMPRISING A CARBINOL COMBINED TO AT LEAST AN NSAID | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2007-01-31 | — | — | EP | claimed |
| WO-2005097099-A1 | ACTIVE SUBSTANCE COMBINATION COMPRISING A CARBINOL COMBINED TO AT LEAST AN NSAID | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2005-10-20 | — | — | WO | claimed |
| EP-1755678-A2 | ACTIVE SUBSTANCE COMBINATION OF A CARBINOL COMPOUND AND AN OPIOID | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2007-02-28 | — | — | EP | disclosed |
| WO-2005097192-A2 | ACTIVE SUBSTANCE COMBINATION OF A CARBINOL COMPOUND AND AN OPIOID | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2005-10-20 | — | — | WO | disclosed |