Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4573808 | 0.66 | CYP3A4 (0.57) | CYP3A4CYP2C9CYP2C19MAPTMEN1 | |
| SCHEMBL12740534 | 0.62 | LMNA (0.31) | LMNA | |
| SCHEMBL11260143 | 0.59 | MEN1 (0.49) | CYP3A4CYP2C9CYP2C19MAPTMEN1 | |
| SCHEMBL9736099 | 0.57 | MAPT (0.47) | CYP3A4CYP2C9CYP2C19MAPTMEN1 | |
| SCHEMBL6628209 | 0.56 | POLB (0.46) | CYP3A4CYP2C9CYP2C19MAPTMEN1 | |
| SCHEMBL593548 | 0.56 | MEN1 (0.43) | CYP3A4CYP2C9CYP2C19MAPTMEN1 | |
| P-Cymene SCHEMBL27525277 | 0.55 | CYP2C9 (0.50) | CYP2C9MAPTALDH1A1KDM4ELMNA | |
| SCHEMBL20033931 | 0.54 | GSK3A (0.46) | CYP2C19MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL5610745 | 0.54 | — | — | |
| Isopropylbenzene SCHEMBL8104018 | 0.53 | CYP2D6 (0.50) | CYP2C9KMT2AKDM4EHPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7273940-B2 | Catalysts for the polymerization of unsaturated compounds | BASELL POLYOLEFINE GMBH (DE) | 2007-09-25 | — | — | US | disclosed |
| US-20050085527-A1 | Catalysts for the polymerization of unsaturated compounds | EQUISTAR CHEMICALS, LP | 2005-04-21 | — | — | US | disclosed |
| US-6818715-B1 | LIGAND SYSTEM FOR NOVEL COMPLEXES CONTAINING LATE TRANSITION METALS WHICH CAN BE USED FOR POLYMERIZATION OF UNSATURATED COMPOUNDS AND GIVE BRANCHED POLYMERS | BASF AKTIENGESELLSCHAFT (DE) | 2004-11-16 | — | — | US | disclosed |
| EP-1204668-B1 | BISIMIDINO COMPOUNDS AND THE TRANSITIONAL METAL COMPLEXES THEREOF AS WELL AS THE USE THEREOF AS CATALYSTS | BASF AG (DE) | 2003-04-02 | — | — | EP | disclosed |
| EP-1204668-A1 | BISIMIDINO COMPOUNDS AND THE TRANSITIONAL METAL COMPLEXES THEREOF AS WELL AS THE USE THEREOF AS CATALYSTS | BASF AKTIENGESELLSCHAFT (DE) | 2002-05-15 | — | — | EP | disclosed |
| WO-2001014391-A1 | BISIMIDINO COMPOUNDS AND THE TRANSITIONAL METAL COMPLEXES THEREOF AS WELL AS THE USE THEREOF AS CATALYSTS | BASF AKTIENGESELLSCHAFT (DE) | 2001-03-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050085527-A1 | Catalysts for the polymerization of unsaturated compounds | NR0B2, NR4A1, CBR1 | CYP3A4 1172/4885CYP2C9 1434/4885CYP2C19 2297/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.