Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB1 | P20618 | 1/20 | 0.48 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 11/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 9/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5600674 | 0.91 | PSMB1 (0.51) | PSMB1PSMB5KMT2AMEN1ALDH1A1 | |
| SCHEMBL5599393 | 0.77 | PSMB1 (0.40) | PSMB1PSMB5KMT2AMEN1ALDH1A1 | |
| SCHEMBL5600030 | 0.66 | CYP3A4 (0.43) | KMT2AMEN1TSHRHRH3SLC6A4 | |
| SCHEMBL6655024 | 0.65 | PSMB1 (0.78) | PSMB1PSMB5KMT2AMEN1ALDH1A1 | |
| SCHEMBL5601407 | 0.64 | MEN1 (0.44) | KMT2AMEN1LMNAMAPTTSHR | |
| SCHEMBL5599453 | 0.64 | HRH3 (0.43) | PSMB1PSMB5HRH3SLC6A4LTA4H | |
| SCHEMBL5599192 | 0.64 | LMNA (0.36) | KMT2ALMNAMAPT | |
| SCHEMBL12204133 | 0.63 | PSMB1 (0.83) | PSMB1PSMB5KMT2AMEN1ALDH1A1 | |
| SCHEMBL8697896 | 0.62 | KMT2A (0.53) | KMT2AALDH1A1TSHRHRH3 | |
| SCHEMBL6654256 | 0.62 | MEN1 (0.33) | KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1755678-A2 | ACTIVE SUBSTANCE COMBINATION OF A CARBINOL COMPOUND AND AN OPIOID | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2007-02-28 | — | — | EP | disclosed |
| WO-2005097192-A2 | ACTIVE SUBSTANCE COMBINATION OF A CARBINOL COMPOUND AND AN OPIOID | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2005-10-20 | — | — | WO | disclosed |