SCHEMBL5599720

SCHEMBL5599720

CO[Si](CCCN1C(=O)C=C(C)C1=O)(OC)OC

nearest known ligand 0.33

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
HSD17B10 Q99714 1/20 0.31
FAAH O00519 1/20 0.31
MGLL Q99685 1/20 0.31
ALDH1A1 P00352 1/20 0.30
POLB P06746 1/20 0.30
PKM P14618 1/20 0.30
TSHR P16473 1/20 0.30
DRD2 P14416 1/20 0.30
DRD3 P35462 1/20 0.30
XPO1 O14980 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14444557 0.84 POLB (0.34) FAAHMGLLPOLBPKMTSHR
SCHEMBL8885500 0.80 MGLL (0.41) MEN1KMT2AFAAHMGLLALDH1A1
SCHEMBL8883684 0.80 MGLL (0.46) MEN1KMT2AFAAHMGLLALDH1A1
SCHEMBL8886103 0.79 MGLL (0.48) MEN1KMT2AFAAHMGLLALDH1A1
SCHEMBL8443620 0.79 MGLL (0.48) MEN1KMT2AFAAHMGLLALDH1A1
SCHEMBL8887050 0.79 MGLL (0.48) MEN1KMT2AFAAHMGLLALDH1A1
SCHEMBL8442748 0.79 MGLL (0.48) MEN1KMT2AFAAHMGLLALDH1A1
SCHEMBL8885012 0.79 MGLL (0.48) MEN1KMT2AFAAHMGLLALDH1A1
SCHEMBL907802 0.79 MGLL (0.48) MEN1KMT2AFAAHMGLLALDH1A1
SCHEMBL8886884 0.79 MGLL (0.48) MEN1KMT2AFAAHMGLLALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7199249-B2 Free radically polymerizable coupling agents HENKEL CORPORATION (US) 2007-04-03 US disclosed
US-20050288457-A1 Co-curable compositions LIU PUWEI 2005-12-29 US disclosed
WO-2004037878-A2 CO-CURABLE COMPOSITIONS HENKEL CORPORATION (US) 2004-05-06 WO disclosed
WO-2004005392-A2 MALEIMIDOPROPYL TRIMETHOXYSILANE AND RELATED FREE-RADICALLY POLYMERIZABLE COUPLING AGENTS AS ADHESION PROMOTORS IN ADHESIVE FORMULATIONS HENKEL LOCTITE CORPORATION (US) 2004-01-15 WO disclosed
US-20040006166-A1 Free radically polymerizable coupling agents HENKEL LOCTITE CORPORATION 2004-01-08 US disclosed