Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | PDE5A | O76074 | 6/20 | 0.55 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.54 |
| ▸ | SLC12A5 | Q9H2X9 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.54 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.51 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.51 |
| ▸ | PDE1A | P54750 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3597144 | 0.86 | SMN1; SMN2 (0.57) | SMN1; SMN2KDM4EGAAMEN1KMT2A | |
| SCHEMBL3607475 | 0.78 | PDE5A (0.70) | KDM4EPDE5APDE1APDE1BPDE1C | |
| SCHEMBL5604178 | 0.78 | MEN1 (0.61) | KDM4EGAAMEN1KMT2AMAPT | |
| SCHEMBL8249057 | 0.77 | HDAC1 (0.53) | SMN1; SMN2KDM4EGAAMEN1KMT2A | |
| SCHEMBL5599931 | 0.75 | PDE5A (0.53) | SMN1; SMN2KDM4EGAAMEN1KMT2A | |
| SCHEMBL17444763 | 0.73 | MEN1 (0.81) | SMN1; SMN2KDM4EGAAMEN1KMT2A | |
| SCHEMBL25720785 | 0.73 | PDE5A (0.79) | SMN1; SMN2KDM4EMEN1KMT2AMAPT | |
| SCHEMBL92487 | 0.72 | ELOVL1 (0.65) | GAAMEN1KMT2ALMNAPDE5A | |
| SCHEMBL5155280 | 0.71 | ITGB1 (0.77) | SMN1; SMN2GAAMAPTALDH1A1LMNA | |
| SCHEMBL465934 | 0.71 | SMN1; SMN2 (0.51) | SMN1; SMN2KDM4EGAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007017728-A2 | NOVEL HETEROCYCLIC COMPOUNDS | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-02-15 | — | — | WO | claimed |
| WO-2007017728-A2 | NOVEL HETEROCYCLIC COMPOUNDS | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-02-15 | — | — | WO | disclosed |