Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELOVL1 | Q9BW60 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | PRKACA | P17612 | 1/20 | 0.61 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | GLS | O94925 | 1/20 | 0.58 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.56 |
| ▸ | CDK2 | P24941 | 1/20 | 0.56 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.56 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.56 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.56 |
| ▸ | RORC | P51449 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | APP | P05067 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.54 |
| ▸ | SLC12A5 | Q9H2X9 | 1/20 | 0.54 |
| ▸ | PDE5A | O76074 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10084284 | 0.86 | MEN1 (0.67) | MEN1KMT2ATP53HSD17B10PDE5A | |
| SCHEMBL9834404 | 0.86 | ELOVL1 (0.65) | ELOVL1MEN1KMT2APRKACAROCK1 | |
| SCHEMBL10082482 | 0.84 | PDE5A (0.68) | MEN1KMT2APDE5APDE1APDE1B | |
| SCHEMBL10084292 | 0.83 | CSNK1D (0.57) | ELOVL1MEN1KMT2AGAAHSD17B10 | |
| SCHEMBL28268613 | 0.83 | RAB9A (0.75) | ELOVL1MEN1KMT2APRKACAROCK1 | |
| SCHEMBL91397 | 0.81 | ROCK2 (0.62) | MEN1KMT2AROCK1LMNATP53 | |
| SCHEMBL10084516 | 0.80 | SMN1; SMN2 (0.62) | MEN1KMT2ALMNATP53HSD17B10 | |
| SCHEMBL91391 | 0.80 | KDM4E (0.69) | MEN1KMT2ACDK5HSD17B10PDE5A | |
| SCHEMBL77834 | 0.80 | KMT2A (0.77) | ELOVL1MEN1KMT2APRKACAROCK1 | |
| SCHEMBL10084285 | 0.80 | ELOVL1 (0.64) | ELOVL1MEN1KMT2APRKACAROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129415-B2 | Fungicide hydroximoyl-tetrazole derivatives | BAYER CROPSCIENCE AG (DE) | 2012-03-06 | — | — | US | disclosed |
| US-8119645-B2 | Fungicide hydroximoyl-tetrazole derivatives | BAYER CROPSCIENCE AG (DE) | 2012-02-21 | — | — | US | disclosed |
| US-20090291969-A1 | Fungicide hydroximoyl-tetrazole derivatives | BAYER CROPSCIENCE AG (DE) | 2009-11-26 | — | — | US | disclosed |
| US-20090192196-A1 | Fungicide hydroximoyl-tetrazole derivatives | BAYER CROPSCIENCE AG (DE) | 2009-07-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090192196-A1 | Fungicide hydroximoyl-tetrazole derivatives | HAAO, HAO1, CYP51A1 | ELOVL1 3631/4885MEN1 930/4885KMT2A 609/4885 |
| US-20090291969-A1 | Fungicide hydroximoyl-tetrazole derivatives | HAAO, HAO1, CYP51A1 | ELOVL1 3631/4885MEN1 938/4885KMT2A 663/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.