Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5317911 | 0.80 | DPP4 (0.34) | ALDH1A1MEN1KMT2AHTTKDM4E | |
| SCHEMBL283987 | 0.76 | ALDH1A1 (0.38) | ALDH1A1MEN1KMT2AHTTKDM4E | |
| SCHEMBL1005413 | 0.74 | ADRB1 (0.48) | ALDH1A1MEN1KMT2AMAPTTSHR | |
| SCHEMBL1005411 | 0.74 | TSHR (0.47) | ALDH1A1KMT2AKDM4EMAPTCRHBP | |
| SCHEMBL17502571 | 0.73 | L3MBTL1 (0.32) | MAPTL3MBTL1 | |
| SCHEMBL1155762 | 0.68 | CYP2A6 (0.38) | ALDH1A1MEN1KMT2AHTTKDM4E | |
| SCHEMBL623218 | 0.68 | TDP1 (0.55) | ALDH1A1MEN1KMT2AHTTKDM4E | |
| SCHEMBL15462283 | 0.68 | ALDH1A1 (0.61) | ALDH1A1MEN1KMT2AHTTKDM4E | |
| SCHEMBL6099464 | 0.68 | POLB (0.40) | ALDH1A1MEN1KMT2AHTTKDM4E | |
| SCHEMBL9706402 | 0.67 | ALDH1A1 (0.42) | ALDH1A1MEN1KMT2AHTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10081587-B2 | Methods for the synthesis of olefins and derivatives | GENOMATICA, INC. (US) | 2018-09-25 | — | — | US | claimed |
| US-20170008828-A1 | METHODS FOR THE SYNTHESIS OF OLEFINS AND DERIVATIVES | GENOMATICA, INC. | 2017-01-12 | — | — | US | claimed |
| US-20090155866-A1 | METHODS FOR THE SYNTHESIS OF OLEFINS AND DERIVATIVES | GENOMATICA, INC. | 2009-06-18 | — | — | US | claimed |
| US-7268233-B2 | Nickel-carbene, palladium-carbene and platinum-carbene complexes, their production and use in catalytic reactions | UMICORE AG & CO. KG (DE) | 2007-09-11 | — | — | US | claimed |
| EP-1526917-B1 | NOVEL NICKEL-CARBENE, PALLADIUM-CARBENE AND PLATINUM-CARBENE COMPLEXES, THEIR PRODUCTION AND USE IN CATALYTIC REACTIONS | UMICORE AG & CO KG (DE) | 2007-03-14 | — | — | EP | claimed |
| US-20060122398-A1 | Novel nickel-carbene, palladium-carbene and platinum-carbene complexes, their produciton and use in catalytic reactions | UMICORE AG & CO. KG (DE) | 2006-06-08 | — | — | US | claimed |
| EP-1526917-A2 | NOVEL NICKEL-CARBENE, PALLADIUM-CARBENE AND PLATINUM-CARBENE COMPLEXES, THEIR PRODUCTION AND USE IN CATALYTIC REACTIONS | Umicore AG & Co. KG (DE) | 2005-05-04 | — | — | EP | claimed |
| WO-2004014550-A2 | NOVEL NICKEL-CARBENE, PALLADIUM-CARBENE AND PLATINUM-CARBENE COMPLEXES, THEIR PRODUCTION AND USE IN CATALYTIC REACTIONS | UMICORE AG & CO. KG (DE) | 2004-02-19 | — | — | WO | claimed |
| WO-2012021093-A1 | METHOD FOR REMOVING WEAKLY SOLUBLE DEPOSITS OF A HIGH‑MOLECULAR‑WEIGHT POLYMER FROM POLYMERIZATION EQUIPMENT (VARIANT EMBODIMENTS) | ЗАКРЫТОЕ АКЦИОНЕРНОЕ ОБЩЕСТВО "СИБУР ХОЛДИНГ" (RU) | 2012-02-16 | — | — | WO | disclosed |
| WO-2011149388-A1 | RUTHENIUM CATALYST FOR THE METATHESIS POLYMERIZATION OF DICYCLOPENTADIENE (EMBODIMENTS) AND METHOD FOR PRODUCING POLYDICYCLOPENTADIENE (EMBODIMENTS) | ЗАКРЫТОЕ АКЦИОНЕРНОЕ ОБЩЕСТВО "СИБУР ХОЛДИНГ" (RU) | 2011-12-01 | — | — | WO | disclosed |
| US-7964758-B2 | Process for production of 2-(substituted phenyl)-3,3,3-trifluoropropene compound | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2011-06-21 | — | — | US | disclosed |
| US-20100160683-A1 | Process for Production of 2-(Substituted Phenyl)-3,3,3-Trifluoropropene Compound | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2010-06-24 | — | — | US | disclosed |
| US-7268233-B2 | Nickel-carbene, palladium-carbene and platinum-carbene complexes, their production and use in catalytic reactions | UMICORE AG & CO. KG (DE) | 2007-09-11 | — | — | US | disclosed |
| EP-1526917-B1 | NOVEL NICKEL-CARBENE, PALLADIUM-CARBENE AND PLATINUM-CARBENE COMPLEXES, THEIR PRODUCTION AND USE IN CATALYTIC REACTIONS | UMICORE AG & CO KG (DE) | 2007-03-14 | — | — | EP | disclosed |
| US-20060122398-A1 | Novel nickel-carbene, palladium-carbene and platinum-carbene complexes, their produciton and use in catalytic reactions | UMICORE AG & CO. KG (DE) | 2006-06-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170008828-A1 | METHODS FOR THE SYNTHESIS OF OLEFINS AND DERIVATIVES | COASY, MTHFD2, FAH | ALDH1A1 232/4885MEN1 243/4885KMT2A 2174/4885 |
| US-20090155866-A1 | METHODS FOR THE SYNTHESIS OF OLEFINS AND DERIVATIVES | COASY, MTHFD2, FAH | ALDH1A1 232/4885MEN1 243/4885KMT2A 2174/4885 |
| US-10081587-B2 | Methods for the synthesis of olefins and derivatives | COASY, MTHFD2, FAH | ALDH1A1 232/4885MEN1 243/4885KMT2A 2174/4885 |
| US-20100160683-A1 | Process for Production of 2-(Substituted Phenyl)-3,3,3-Trifluoropropene Compound | PEX3, SCO2, LPO | ALDH1A1 3618/4885MEN1 1622/4885KMT2A 2764/4885 |
| US-20060122398-A1 | Novel nickel-carbene, palladium-carbene and platinum-carbene complexes, their produciton and use in catalytic reactions | PPOX, PDCD1, PDCD1LG2 | ALDH1A1 3436/4885MEN1 98/4885KMT2A 2773/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.