⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14335902 | 0.81 | LMNA (0.32) | — | |
| SCHEMBL25170610 | 0.80 | — | — | |
| SCHEMBL9015022 | 0.78 | TSHR (0.34) | — | |
| SCHEMBL25170631 | 0.76 | MAPT (0.34) | — | |
| SCHEMBL28848001 | 0.74 | — | — | |
| SCHEMBL25169841 | 0.74 | MAPT (0.37) | — | |
| SCHEMBL25176273 | 0.74 | MAPT (0.37) | — | |
| SCHEMBL5696403 | 0.69 | TRPA1 (0.33) | — | |
| SCHEMBL11222121 | 0.68 | — | — | |
| SCHEMBL19004724 | 0.66 | TSHR (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1771490-A1 | BIOCOMPATIBLE, BIODEGRADABLE POLYURETHANE MATERIALS WITH CONTROLLED HYDROPHOBIC TO HYDROPHILIC RATIO | Synthes GmbH (CH) | 2007-04-11 | — | — | EP | claimed |
| WO-2006010278-A1 | BIOCOMPATIBLE, BIODEGRADABLE POLYURETHANE MATERIALS WITH CONTROLLED HYDROPHOBIC TO HYDROPHILIC RATIO | SYNTHES GMBH (CH) | 2006-02-02 | — | — | WO | claimed |
| EP-1771490-A1 | BIOCOMPATIBLE, BIODEGRADABLE POLYURETHANE MATERIALS WITH CONTROLLED HYDROPHOBIC TO HYDROPHILIC RATIO | Synthes GmbH (CH) | 2007-04-11 | — | — | EP | disclosed |
| WO-2006010278-A1 | BIOCOMPATIBLE, BIODEGRADABLE POLYURETHANE MATERIALS WITH CONTROLLED HYDROPHOBIC TO HYDROPHILIC RATIO | SYNTHES GMBH (CH) | 2006-02-02 | — | — | WO | disclosed |