Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 6/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.36 |
| ▸ | MPL | P40238 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5602449 | 0.79 | HSD11B1 (0.40) | HSD11B1NOTUMCYP1A2CYP3A4 | |
| SCHEMBL5603316 | 0.74 | CYP1A2 (0.37) | HSD11B1NOTUMSCN9APSMB8CYP1A2 | |
| SCHEMBL5602458 | 0.72 | HSD11B1 (0.35) | HSD11B1 | |
| SCHEMBL5601672 | 0.69 | IDO1 (0.38) | — | |
| SCHEMBL6897661 | 0.69 | CYP2A6 (0.38) | HSD11B1NOTUMCYP1A2 | |
| SCHEMBL5601783 | 0.69 | GABRA1 (0.39) | CYP1A2CYP3A4 | |
| SCHEMBL197671 | 0.69 | HSD11B1 (0.56) | HSD11B1NOTUMPSMB8CYP1A2CYP3A4 | |
| SCHEMBL24062 | 0.68 | MEN1 (0.37) | CES1CYP1A2CYP3A4 | |
| SCHEMBL5602257 | 0.68 | NPC1 (0.41) | NOTUMCYP1A2CYP3A4 | |
| SCHEMBL5603289 | 0.68 | HSD11B1 (0.36) | HSD11B1NOTUMMPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7276567-B2 | Heterocyclic substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2007-10-02 | — | — | US | claimed |
| US-7276567-B2 | Heterocyclic substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2007-10-02 | — | — | US | disclosed |
| US-20050261449-A1 | Heterocyclic substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENT INC. | 2005-11-24 | — | — | US | disclosed |