SCHEMBL560071

SCHEMBL560071

Oc1ccccc1Cc1ccc(Cl)cc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KEAP1 Q14145 1/20 0.70
MEN1 O00255 3/20 0.61
KMT2A Q03164 3/20 0.61
HIF1A Q16665 3/20 0.61
MAPT P10636 2/20 0.61
CYP3A4 P08684 2/20 0.61
HPGD P15428 2/20 0.61
ALOX15 P16050 2/20 0.61
HSD17B10 Q99714 1/20 0.61
HSPA5 P11021 2/20 0.60
HSP90AA1 P07900 2/20 0.47
LMNA P02545 2/20 0.47
HTT P42858 2/20 0.47
BCL2 P10415 1/20 0.47
BCL2L1 Q07817 1/20 0.47
SLC22A1 O15245 1/20 0.47
USP2 O75604 1/20 0.47
HSPD1 P10809 1/20 0.47
IDO1 P14902 1/20 0.47
ALOX12 P18054 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9776607 0.89 KEAP1 (0.86) KEAP1MEN1KMT2AHIF1ACYP3A4
SCHEMBL30616875 0.89 KEAP1 (0.86) KEAP1MEN1KMT2AHIF1ACYP3A4
SCHEMBL8925742 0.83 KEAP1 (0.76) KEAP1MEN1KMT2AHIF1ACYP3A4
SCHEMBL29506902 0.83 KEAP1 (1.00) KEAP1MEN1KMT2AHIF1AMAPT
SCHEMBL68653 0.83 KEAP1 (1.00) KEAP1MEN1KMT2AHIF1AMAPT
SCHEMBL87816 0.82 KEAP1 (0.75) KEAP1MEN1KMT2AHIF1ACYP3A4
SCHEMBL30335116 0.82 KEAP1 (0.75) KEAP1MEN1KMT2AHIF1ACYP3A4
SCHEMBL8707170 0.82 AKR1B1 (0.53) KEAP1MEN1KMT2AHIF1ACYP3A4
SCHEMBL920838 0.81 KEAP1 (0.96) KEAP1MEN1KMT2AHIF1AMAPT
SCHEMBL28998999 0.80 KEAP1 (0.72) KEAP1MEN1KMT2AHIF1ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090105195-A1 COMPOSITION COMPRISING MICROBICIDAL ACTIVE INGREDIENTS NUGENE BIOPHARMA, INC 2009-04-23 US claimed
CN-116888249-A Effervescent bactericidal composition 雷克特和科尔曼(海外)家用卫生有限公司 2023-10-13 CN disclosed
CN-107750124-B Antimicrobial compositions and methods for reducing microbial contamination 波利维逊有限公司 2022-10-28 CN disclosed
US-11279835-B2 Antifouling coating composition comprising novel carbon-based hydrolysable polymers HEMPEL A/S (DK) 2022-03-22 US disclosed
CN-110139903-B Antifouling coating composition comprising novel carbon-based hydrolysable polymers 汉伯公司 2022-01-28 CN disclosed
US-20210163758-A1 ANTIFOULING COATING COMPOSITION COMPRISING NOVEL CARBON-BASED HYDROLYSABLE POLYMERS HEMPEL A/S (DK) 2021-06-03 US disclosed
EP-3724278-A1 CONTROLLED RELEASE ANTIFOULING COATING COMPOSITION VIA BIOCIDE INTERACTION Hempel A/S (DK) 2020-10-21 EP disclosed
EP-3700985-A1 SELF-POLISHING ANTIFOULING COATING COMPOSITION COMPRISING ALKOXYSILANE Hempel A/S (DK) 2020-09-02 EP disclosed
EP-3538615-A1 AN ANTIFOULING COATING COMPOSITION COMPRISING NOVEL CARBON-BASED HYDROLYSABLE POLYMERS Hempel A/S (DK) 2019-09-18 EP disclosed
WO-2019115747-A1 CONTROLLED RELEASE ANTIFOULING COATING COMPOSITION VIA BIOCIDE INTERACTION HEMPEL A/S (DK) 2019-06-20 WO disclosed
EP-0286243-A1 Disintegration type resin particles, its preparation and coating composition containing the same Nippon Paint Co., Ltd. (JP) 1988-10-12 EP disclosed
US-4774080-A ACRYLIC RESIN, POLYESTER OR EPOXY RESIN NIPPON PAINT CO., LTD. (JP) 1988-09-27 US disclosed
EP-0220965-A2 Resinous composition capable of releasing a bioactive substance at a controlled rate Nippon Paint Co., Ltd. (JP) 1987-05-06 EP disclosed
EP-0204456-A1 A hydrolyzable resin composition and an antifouling coating composition containing the same Nippon Paint Co., Ltd. (JP) 1986-12-10 EP disclosed
US-4562211-A ANTIDEPRESSANTS MITSUBISHI CHEMICAL INDUSTRIES, LTD. (JP) 1985-12-31 US disclosed
EP-0014493-B1 CHLOROBENZYL PHENOXY ALKANOIC COMPOUNDS SIEGFRIED AKTIENGESELLSCHAFT (CH) 1982-12-29 EP disclosed
EP-0014493-A1 Chlorobenzyl phenoxy alkanoic compounds SIEGFRIED AKTIENGESELLSCHAFT (CH) 1980-08-20 EP disclosed
US-4214095-A ANTILIPEMIC, ANTICHOLESTEROL SIEGFRIED AKTIENGESELLSCHAFT (CH) 1980-07-22 US disclosed
US-4069340-A ARYLOXY DIMETHYL IMMONIUM CHLORIDES FROM DIMETHYL FORMAMIDE AND CORRESPONDING ARYL CHLOROFORMATES HOOKER CHEMICALS & PLASTICS CORPORATION (US) 1978-01-17 US disclosed
US-3983178-A Immonium salts and derivatives thereof HOOKER CHEMICALS & PLASTICS CORPORATION (US) 1976-09-28 US disclosed