SCHEMBL5600846

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL415446	0.85	HDAC3 (0.60)	CHRNA7TACR2HDAC1HDAC3HDAC4
	SCHEMBL5600774	0.83	HDAC3 (0.57)	TACR2HDAC1HDAC3HDAC4HDAC7
	SCHEMBL1837268	0.82	HDAC3 (0.56)	TACR2HDAC1HDAC3HDAC4HDAC7
	SCHEMBL5599694	0.76	DHODH (0.47)	MEN1RAB9AKMT2A
	SCHEMBL3428350	0.74	CTSL (0.62)	MEN1RAB9AKMT2A
	SCHEMBL20612373	0.73	LMNA (0.54)	CHRNA7MEN1RAB9AKMT2ADHPS
	SCHEMBL30151656	0.73	BCL2L1 (0.59)	CHRNA7MEN1RAB9AKMT2ADHPS
	SCHEMBL498133	0.73	BCL2L1 (0.59)	CHRNA7MEN1RAB9AKMT2ADHPS
	SCHEMBL17433469	0.72	MEN1 (0.61)	CHRNA7MEN1RAB9AKMT2ADHPS
	SCHEMBL22869806	0.70	MEN1 (0.48)	MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.