Indole

Indole

SCHEMBL560095

CC(=O)C(=O)O.c1ccc2[nH]ccc2c1

nearest known ligand 0.65

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.65
CA1 P00915 1/20 0.65
CA2 P00918 1/20 0.65
ITGB2 P05107 1/20 0.65
ICAM1 P05362 1/20 0.65
ITGAL P20701 1/20 0.65
CA4 P22748 1/20 0.65
CA6 P23280 1/20 0.65
AHR P35869 1/20 0.65
ADK P55263 1/20 0.65
KDM4E B2RXH2 2/20 0.46
HPGD P15428 2/20 0.46
HSD17B10 Q99714 2/20 0.46
ALDH1A1 P00352 1/20 0.46
ENPP2 Q13822 1/20 0.46
CTNNB1 P35222 2/20 0.45
WNT3A P56704 2/20 0.45
MAPT P10636 3/20 0.44
NPC1 O15118 2/20 0.44
RAB9A P51151 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Indole SCHEMBL31119874 1.00 TRPA1 (0.65) TRPA1CA1CA2ITGB2ICAM1
Indole SCHEMBL15552 0.92 TRPA1 (0.71) TRPA1CA1CA2ITGB2ICAM1
Indole SCHEMBL28064106 0.92 TRPA1 (0.71) TRPA1CA1CA2ITGB2ICAM1
Indole SCHEMBL8692212 0.92 TRPA1 (0.71) TRPA1CA1CA2ITGB2ICAM1
Indole SCHEMBL14576595 0.90 TRPA1 (0.68) TRPA1CA1CA2ITGB2ICAM1
Indole SCHEMBL14576774 0.90 TRPA1 (0.68) TRPA1CA1CA2ITGB2ICAM1
Indole SCHEMBL14576591 0.90 TRPA1 (0.68) TRPA1CA1CA2ITGB2ICAM1
Indole SCHEMBL14576309 0.90 TRPA1 (0.68) TRPA1CA1CA2ITGB2ICAM1
Indole SCHEMBL14576777 0.90 TRPA1 (0.68) TRPA1CA1CA2ITGB2ICAM1
Naphthalene SCHEMBL29066893 0.90 TRPA1 (0.68) TRPA1CA1CA2ITGB2ICAM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 389 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3690042-B1 PARTHENOCARPY REGULATION GENE AND USE THEREOF NATIONAL RES AND DEVELOPMENT AGENCY NATIONAL AGRICULTURE AND FOOD RES ORGANIZATION (JP) 2026-05-06 EP claimed
EP-3796922-B1 PHARMACEUTICAL COMPOSITIONS COMPRISING A SELENO AMINO ACID COMPOUND FOR USE IN COMBINATION WITH ANOTHER AGENT FOR THE TREATMENT OF LIVER OR PANCREAS CANCER SELEQ OY (FI) 2026-03-18 EP claimed
US-12310936-B2 Pharmaceutical compositions for the treatment of cancer SELEQ OY (FI) 2025-05-27 US claimed
CN-119816897-A Multiple study assessment 普罗科技有限公司 2025-04-11 CN claimed
CN-118486893-A Amino acid eutectic electrolyte, and preparation method and application thereof 江苏蓝固新能源科技有限公司 2024-08-13 CN claimed
CN-114674956-A Application of urine biomarker detection reagent in preparation of kit for predicting neuropsychiatric sequelae of new coronary pneumonia 重庆医科大学附属第一医院 2022-06-28 CN claimed
EP-3095863-B1 PARTHENOCARPY REGULATION GENE AND USE THEREOF NATIONAL RES AND DEVELOPMENT AGENCY NATIONAL AGRICULTURE AND FOOD RES ORGANIZATION (JP) 2022-03-09 EP claimed
US-11091773-B2 Parthenocarpy regulation gene and use thereof NATIONAL RESEARCH AND DEVELOPMENT AGENCY NATIONAL AGRICULTURE AND FOOD RESEARCH ORGANIZATION (JP) 2021-08-17 US claimed
US-20210220310-A1 PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF CANCER SELEQ OY (FI) 2021-07-22 US claimed
EP-3796922-A1 PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF CANCER Seleq Oy (FI) 2021-03-31 EP claimed
WO-2009144699-A1 METHODS OF TREATING CANCER OF THE CENTRAL NERVOUS SYSTEM YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2009-12-03 WO claimed
US-20090011476-A1 GENE CLUSTER AND METHOD FOR THE BIOSYNTHESIS OF TERREQUINONE A WISCONSIN ALUMNI RESEARCH FOUNDATION 2009-01-08 US claimed
EP-2007206-A2 METHOD AND COMPOSITION FOR PROTECTING NEURONAL TISSUE FROM DAMAGE INDUCED BY ELEVATED GLUTAMINE LEVELS YEDA RESEARCH AND DEVELOPMENT CO., LTD. (IL) 2008-12-31 EP claimed
WO-2007105203-A2 METHOD AND COMPOSITION FOR PROTECTING NEURONAL TISSUE FROM DAMAGE INDUCED BY ELEVATED GLUTAMATE LEVELS YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2007-09-20 WO claimed
US-20060024284-A1 Method and composition for protecting neuronal tissue from damage induced by elevated glutamate levels YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2006-02-02 US claimed
EP-1524989-A2 METHOD AND COMPOSITION FOR PROTECTING NEURONAL TISSUE FROM DAMAGE INDUCED BY ELEVATED GLUTAMATE LEVELS YEDA RESEARCH AND DEVELOPMENT Co. LTD. (IL) 2005-04-27 EP claimed
WO-2004012762-A2 METHOD AND COMPOSITION FOR PROTECTING NEURONAL TISSUE FROM DAMAGE INDUCED BY ELEVATED GLUTAMATE LEVELS YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2004-02-12 WO claimed
US-4859591-A Transamination process for producing amino acids W. R. GRACE & CO.-CONN. (US) 1989-08-22 US claimed
EP-0162920-A1 METHOD OF CATALYZING CHEMICAL REACTIONS IGEN, INC. (a California corporation) (US) 1985-12-04 EP claimed
WO-1985002414-A1 METHOD OF CATALYZING CHEMICAL REACTIONS IGEN, INC. (US) 1985-06-06 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210220310-A1 PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF CANCER RNASE1, SELENOI, GLS2 TRPA1 4500/4885CA1 1479/4885CA2 3013/4885
US-12310936-B2 Pharmaceutical compositions for the treatment of cancer RNASE1, SELENOI, GLS2 TRPA1 4500/4885CA1 1479/4885CA2 3013/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.