SCHEMBL5600980

SCHEMBL5600980

Cc1ccc2c(c1Cc1ccccc1)N=N[N]2

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDH1 O75874 1/20 0.39
CALM1 P0DP23 1/20 0.34
ENPP1 P22413 2/20 0.33
SMN1; SMN2 Q16637 3/20 0.32
NPC1 O15118 2/20 0.32
RAB9A P51151 2/20 0.32
HPGD P15428 1/20 0.32
KDM4E B2RXH2 2/20 0.32
POLB P06746 2/20 0.32
GAA P10253 2/20 0.32
HTT P42858 2/20 0.32
ALDH1A1 P00352 1/20 0.32
NQO1 P15559 1/20 0.31
SHBG P04278 1/20 0.31
MAPK1 P28482 2/20 0.31
TDP1 Q9NUW8 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
TAAR1 Q96RJ0 1/20 0.31
JAK2 O60674 1/20 0.31
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5603703 0.78 NOS3 (0.36)
SCHEMBL5603157 0.75 NOS2 (0.40) HPGDKDM4EPOLBGAAALDH1A1
SCHEMBL5602438 0.72 KCNH2 (0.33) KDM4EALDH1A1SHBGTDP1L3MBTL1
SCHEMBL5602068 0.71 HTR2A (0.39) CALM1SMN1; SMN2HPGD
SCHEMBL5601083 0.71 KMT2A (0.36) SMN1; SMN2NPC1RAB9AHPGDKDM4E
SCHEMBL5601744 0.71 KCNH2 (0.36) KDM4EALDH1A1SHBGTDP1L3MBTL1
SCHEMBL5602743 0.71 KCNH2 (0.36) KDM4EALDH1A1SHBGTDP1L3MBTL1
SCHEMBL5600627 0.71 KCNH2 (0.36) KDM4EALDH1A1SHBGTDP1L3MBTL1
SCHEMBL5603469 0.70 IDH1 (0.38) IDH1CALM1ENPP1SMN1; SMN2NPC1
SCHEMBL9066733 0.69 IDH1 (0.49) IDH1CALM1SMN1; SMN2HPGDKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7276567-B2 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-10-02 US claimed
US-7276567-B2 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-10-02 US disclosed
US-20050261449-A1 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENT INC. 2005-11-24 US disclosed