SCHEMBL5603469

SCHEMBL5603469

Cc1ccc2c(c1Cc1ccccc1)[N]c1ccccc1-2

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDH1 O75874 1/20 0.38
RAB9A P51151 3/20 0.37
SMN1; SMN2 Q16637 3/20 0.37
NPC1 O15118 2/20 0.37
HPGD P15428 1/20 0.37
MAPK1 P28482 3/20 0.36
TDP1 Q9NUW8 2/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
TP53 P04637 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP2D6 P10635 1/20 0.34
TSHR P16473 1/20 0.34
CYP2C19 P33261 1/20 0.34
HIF1A Q16665 1/20 0.34
CLK4 Q9HAZ1 1/20 0.34
CALM1 P0DP23 1/20 0.33
MAOB P27338 1/20 0.33
ENPP1 P22413 2/20 0.32
ALPL P05186 1/20 0.32
KDM4E B2RXH2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5601789 0.83 NOS3 (0.34) RAB9ASMN1; SMN2NPC1MAPK1L3MBTL1
SCHEMBL5600733 0.79 NOS2 (0.37) HPGDKDM4EALDH1A1
SCHEMBL5602143 0.78 HSD11B1 (0.32) HPGDCYP1A2TSHRKDM4EALDH1A1
SCHEMBL5601844 0.77 GPR3 (0.35) TDP1L3MBTL1
SCHEMBL5601851 0.76 GPR3 (0.38)
SCHEMBL5601229 0.76 GPR3 (0.38)
SCHEMBL5600994 0.76 GPR3 (0.38)
SCHEMBL5603226 0.76 GPR3 (0.38)
SCHEMBL5601729 0.76 GPR3 (0.38)
SCHEMBL5600511 0.76 GPR3 (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7276567-B2 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-10-02 US claimed
US-7276567-B2 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-10-02 US disclosed
US-20050261449-A1 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENT INC. 2005-11-24 US disclosed