SCHEMBL5601247

SCHEMBL5601247

CCCCCCCCCC1=N[N]c2cccc(C)c21

nearest known ligand 0.42

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 2/20 0.42
TYR P14679 1/20 0.37
TLR8 Q9NR97 4/20 0.37
CNR1 P21554 1/20 0.35
CNR2 P34972 1/20 0.35
HTR2A P28223 1/20 0.35
DHFR P00374 1/20 0.35
GPR84 Q9NQS5 1/20 0.34
ALOX5 P09917 4/20 0.33
TBXAS1 P24557 1/20 0.33
CYSLTR2 Q9NS75 1/20 0.33
CYSLTR1 Q9Y271 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5600740 1.00 KCNH2 (0.42) KCNH2TYRTLR8CNR1CNR2
SCHEMBL5599722 1.00 KCNH2 (0.42) KCNH2TYRTLR8CNR1CNR2
SCHEMBL5603145 1.00 KCNH2 (0.42) KCNH2TYRTLR8CNR1CNR2
SCHEMBL5599913 1.00 KCNH2 (0.42) KCNH2TYRTLR8CNR1CNR2
SCHEMBL5602752 1.00 KCNH2 (0.42) KCNH2TYRTLR8CNR1CNR2
SCHEMBL5601849 1.00 KCNH2 (0.42) KCNH2TYRTLR8CNR1CNR2
SCHEMBL5603673 0.98 KCNH2 (0.40) KCNH2TYRTLR8CNR1CNR2
SCHEMBL5602421 0.94 TLR8 (0.35) KCNH2TLR8CNR1CNR2
SCHEMBL5600946 0.87 NOS2 (0.33) KCNH2TLR8HTR2A
SCHEMBL5602033 0.84 LIPG (0.42) KCNH2TYRTLR8ALOX5CYSLTR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7276567-B2 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-10-02 US claimed
US-7276567-B2 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-10-02 US disclosed
US-20050261449-A1 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENT INC. 2005-11-24 US disclosed