Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 8/20 | 0.38 |
| ▸ | TYR | P14679 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | DHFR | P00374 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | GCGR | P47871 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5599913 | 0.98 | KCNH2 (0.42) | KCNH2TLR8TYRALOX5CNR1 | |
| SCHEMBL5600740 | 0.98 | KCNH2 (0.42) | KCNH2TLR8TYRALOX5CNR1 | |
| SCHEMBL5603145 | 0.98 | KCNH2 (0.42) | KCNH2TLR8TYRALOX5CNR1 | |
| SCHEMBL5602752 | 0.98 | KCNH2 (0.42) | KCNH2TLR8TYRALOX5CNR1 | |
| SCHEMBL5601247 | 0.98 | KCNH2 (0.42) | KCNH2TLR8TYRALOX5CNR1 | |
| SCHEMBL5599722 | 0.98 | KCNH2 (0.42) | KCNH2TLR8TYRALOX5CNR1 | |
| SCHEMBL5601849 | 0.98 | KCNH2 (0.42) | KCNH2TLR8TYRALOX5CNR1 | |
| SCHEMBL5602421 | 0.95 | TLR8 (0.35) | KCNH2TLR8MEN1LMNAMAPT | |
| SCHEMBL5600946 | 0.88 | NOS2 (0.33) | KCNH2TLR8LMNAHTR2A | |
| SCHEMBL5601943 | 0.84 | ALOX5 (0.43) | KCNH2TLR8TYRALOX5PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7276567-B2 | Heterocyclic substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2007-10-02 | — | — | US | claimed |
| US-7276567-B2 | Heterocyclic substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2007-10-02 | — | — | US | disclosed |
| US-20050261449-A1 | Heterocyclic substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENT INC. | 2005-11-24 | — | — | US | disclosed |