Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.64 |
| ▸ | HPGD | P15428 | 3/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.64 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.64 |
| ▸ | TTR | P02766 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | USP2 | O75604 | 1/20 | 0.64 |
| ▸ | DHFR | P00374 | 1/20 | 0.64 |
| ▸ | CA1 | P00915 | 1/20 | 0.64 |
| ▸ | CA2 | P00918 | 1/20 | 0.64 |
| ▸ | ALB | P02768 | 1/20 | 0.64 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.64 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.64 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | KDR | P35968 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5603737 | 0.91 | ACMSD (0.54) | ALDH1A1KDM4EHPGDHSD17B10ACMSD | |
| Diflunisal SCHEMBL5603898 | 0.89 | KDM4E (0.55) | ALDH1A1KDM4EHPGDHSD17B10ACMSD | |
| SCHEMBL5603732 | 0.87 | ALDH1A1 (0.57) | ALDH1A1KDM4EHPGDHSD17B10ACMSD | |
| Diflunisal SCHEMBL5603727 | 0.84 | ACMSD (0.78) | ALDH1A1KDM4EHPGDHSD17B10ACMSD | |
| Salsalate SCHEMBL360114 | 0.82 | ACMSD (0.70) | ALDH1A1KDM4EHPGDHSD17B10ACMSD | |
| SCHEMBL831732 | 0.81 | KDM4E (0.64) | ALDH1A1KDM4EHPGDHSD17B10MEN1 | |
| Diflunisal SCHEMBL4337 | 0.79 | ACMSD (1.00) | ALDH1A1KDM4EHPGDHSD17B10ACMSD | |
| Diflunisal SCHEMBL30509654 | 0.79 | ACMSD (1.00) | ALDH1A1KDM4EHPGDHSD17B10ACMSD | |
| Diflunisal SCHEMBL29367380 | 0.79 | ACMSD (1.00) | ALDH1A1KDM4EHPGDHSD17B10ACMSD | |
| Diflunisal SCHEMBL3848363 | 0.79 | ACMSD (1.00) | ALDH1A1KDM4EHPGDHSD17B10ACMSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7183269-B2 | Synergistic compositions for the selective control of tumor tissue | KREUTZ WERNER | 2007-02-27 | — | — | US | disclosed |
| US-20040147493-A1 | Synergistic compositions for the selective control of tumor tissue | KREUTZ WERNER | 2004-07-29 | — | — | US | disclosed |
| US-6727235-B2 | Synergistic mixture comprising benzoic acid derivatives for use as anticarcinogenic agents, antitumor agents | KREUTZ WERNER (DE) | 2004-04-27 | — | — | US | disclosed |
| US-20030166621-A1 | Synergistic mixture comprising benzoic acid derivatives for use as anticarcinogenic agents, antitumor agents | KREUTZ WERNER (DE) | 2003-09-04 | — | — | US | disclosed |
| US-6525038-B1 | Synergistic composition of 5-(2,4-difluorophenyl) salicylic acid and 2-hydroxy-4-aminobenzoic acid | KREUTZ WERNER (DE) | 2003-02-25 | — | — | US | disclosed |
| US-6395720-B1 | ANTICANCER AGENTS | KREUTZ WERNER (DE) | 2002-05-28 | — | — | US | disclosed |