Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 10/20 | 0.37 |
| ▸ | RAB9A | P51151 | 10/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | PKM | P14618 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.36 |
| ▸ | RELA | Q04206 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | HPGDS | O60760 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 5/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5601902 | 0.88 | IDO1 (0.37) | NPC1RAB9ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL3876013 | 0.72 | MEN1 (0.40) | NPC1RAB9ASMN1; SMN2MAPTPKM | |
| SCHEMBL5603935 | 0.72 | NPC1 (0.37) | NPC1RAB9ASMN1; SMN2MAPTPKM | |
| SCHEMBL1091995 | 0.70 | HSD11B1 (0.34) | NPC1RAB9ASMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL8036362 | 0.69 | LMNA (0.50) | NPC1RAB9ASMN1; SMN2MAPTPKM | |
| SCHEMBL12912969 | 0.68 | NPC1 (0.46) | NPC1RAB9ASMN1; SMN2MAPTPKM | |
| SCHEMBL12912867 | 0.68 | IDO1 (0.50) | NPC1RAB9ASMN1; SMN2MAPTPKM | |
| SCHEMBL2962416 | 0.65 | ELANE (0.47) | NPC1RAB9ASMN1; SMN2MAPTKDM4E | |
| SCHEMBL3871108 | 0.65 | ELANE (0.47) | NPC1RAB9ASMN1; SMN2MAPTPKM | |
| SCHEMBL5602494 | 0.65 | NPC1 (0.37) | NPC1RAB9ASMN1; SMN2MAPTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7276567-B2 | Heterocyclic substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2007-10-02 | — | — | US | claimed |
| US-7276567-B2 | Heterocyclic substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2007-10-02 | — | — | US | disclosed |
| US-20050261449-A1 | Heterocyclic substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENT INC. | 2005-11-24 | — | — | US | disclosed |