SCHEMBL3876013

SCHEMBL3876013

Cc1ccc(-c2ccc3c(c2)-c2ccccc2[N]3)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.40
KMT2A Q03164 5/20 0.40
PDK2 Q15119 1/20 0.40
HPRT1 P00492 1/20 0.39
EDNRB P24530 1/20 0.38
EDNRA P25101 1/20 0.38
NPC1 O15118 9/20 0.38
RAB9A P51151 9/20 0.38
PKM P14618 2/20 0.38
TP53 P04637 2/20 0.38
MAPK1 P28482 2/20 0.38
HPGDS O60760 1/20 0.38
TSHR P16473 1/20 0.38
AGTR1 P30556 1/20 0.38
MAPT P10636 4/20 0.36
KDM4E B2RXH2 3/20 0.36
ALDH1A1 P00352 3/20 0.36
HPGD P15428 3/20 0.36
L3MBTL1 Q9Y468 3/20 0.36
TDP1 Q9NUW8 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20553777 0.90 MEN1 (0.38) MEN1KMT2APDK2HPRT1NPC1
SCHEMBL2967623 0.86 MEN1 (0.47) MEN1KMT2APDK2NPC1RAB9A
SCHEMBL20553967 0.86 ENPP3 (0.44) MEN1KMT2APDK2NPC1RAB9A
SCHEMBL2962416 0.84 ELANE (0.47) MEN1KMT2APDK2NPC1RAB9A
SCHEMBL20553844 0.81 TRPA1 (0.45) PDK2EDNRBEDNRAMAPK1TSHR
SCHEMBL20553766 0.81 ABL1 (0.50) PDK2EDNRBEDNRANPC1RAB9A
SCHEMBL3877841 0.81 KIF11 (0.43) MEN1KMT2ANPC1RAB9ATP53
SCHEMBL814578 0.80 MEN1 (0.47) MEN1KMT2ANPC1RAB9AMAPK1
SCHEMBL2954904 0.78 GSTP1 (0.46) NPC1RAB9AMAPTKDM4EALDH1A1
SCHEMBL20553962 0.77 TRPA1 (0.47) PDK2EDNRBEDNRANPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118251380-A Spiro- (indan-fluorene) compounds and their use in organic electronic devices 多蒂肯独家合成控股公司 2024-06-25 CN disclosed
EP-3621946-B1 INDANE DERIVATIVES AND THEIR USE IN ORGANIC ELECTRONICS DOTTIKON ES HOLDING AG (CH) 2023-09-06 EP disclosed
WO-2023078824-A1 SPIRO-(INDANE-FLUORENE) TYPE COMPOUNDS AND THEIR USE IN ORGANIC ELECTRONICS DOTTIKON ES HOLDING AG (CH) 2023-05-11 WO disclosed
CN-110473989-B Method for manufacturing organic light emitting element 株式会社LG化学 2022-05-27 CN disclosed
US-20220006020-A1 DI-, TRI- AND TETRAPHENYLINDANE DERIVATES AND THEIR USE IN ORGANIC ELECTRONICS DOTTIKON ES HOLDING AG (CH) 2022-01-06 US disclosed
EP-3877357-A1 DI-, TRI- AND TETRAPHENYLINDANE DERIVATIVES AND THEIR USE IN ORGANIC ELECTRONICS DOTTIKON ES HOLDING AG (CH) 2021-09-15 EP disclosed
CN-113365976-A Diphenylindane, triphenylindane and tetraphenylindan derivatives and their use in organic devices 多蒂肯独家合成控股公司 2021-09-07 CN disclosed
EP-2657315-B1 ORGANIC LIGHT-EMITTING DEVICE LG CHEMICAL LTD (KR) 2020-12-16 EP disclosed
CN-109923689-B Method for purifying organic substance used as material of organic light-emitting element 株式会社LG化学 2020-06-19 CN disclosed
EP-3650438-A1 DI-, TRI- AND TETRAPHENYLINDANE DERIVATIVES AND THEIR USE IN ORGANIC ELECTRONICS DOTTIKON ES HOLDING AG (CH) 2020-05-13 EP disclosed
US-9349964-B2 Organic light emitting diode and manufacturing method thereof LG CHEM, LTD. (KR) 2016-05-24 US disclosed
EP-2657315-A2 ORGANIC LIGHT-EMITTING DEVICE AND METHOD FOR MANUFACTURING SAME LG Chem, Ltd. (KR) 2013-10-30 EP disclosed
US-20120193612-A1 ORGANIC LIGHT EMITTING DIODE AND MANUFACTURING METHOD THEREOF LG CHEM, LTD. (KR) 2012-08-02 US disclosed
US-7482490-B2 Amine compound having fluorene group as framework, process for producing the amine compound, and use of the amine compound TOSOH CORPORATION (JP) 2009-01-27 US disclosed
US-20080194878-A1 Amine Compound Having Fluorene Group as Framework, Process for Producing the Amine Compound, and Use of the Amine Compound TOSOH CORPORATION (JP) 2008-08-14 US disclosed
US-7189877-B2 Arylamine derivatives having fluorene skeleton, synthetic intermediates thereof, processes of producing those, and organic electrolumivescene devices TOSCH CORPORATION (JP) 2007-03-13 US disclosed
EP-1752440-A1 AMINE COMPOUND HAVING FLUORENE GROUP AS FRAMEWORK, PROCESS FOR PRODUCING THE AMINE COMPOUND, AND USE OF THE AMINE COMPOUND Tosoh Corporation (JP) 2007-02-14 EP disclosed
EP-1400578-B1 Electrolumisescent 9,9-bis(4-amino)-1,1'-biphenyl)fluorene derivatives TOSOH CORP (JP) 2005-11-30 EP disclosed
US-20040110958-A1 Novel arylamine derivatives having fluorene skeleton, synthetic intermediates thereof, processes of producing those, and organic electrolumivescene devices TOSOH CORPORATION 2004-06-10 US disclosed
EP-1400578-A1 Electrolumisescent 9,9-bis(4-amino)-1,1'-biphenyl)fluorene derivatives Tosoh Corporation (JP) 2004-03-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220006020-A1 DI-, TRI- AND TETRAPHENYLINDANE DERIVATES AND THEIR USE IN ORGANIC ELECTRONICS NR0B2, KCNJ2, TRRAP MEN1 2154/4885KMT2A 1970/4885PDK2 1160/4885
US-20040110958-A1 Novel arylamine derivatives having fluorene skeleton, synthetic intermediates thereof, processes of producing those, and organic electrolumivescene devices AHR, NAT1, AR MEN1 3318/4885KMT2A 1459/4885PDK2 2093/4885
US-20080194878-A1 Amine Compound Having Fluorene Group as Framework, Process for Producing the Amine Compound, and Use of the Amine Compound TAAR1, SLC18A1, ADRB2 MEN1 1708/4885KMT2A 2235/4885PDK2 3867/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.