Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 6/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.58 |
| ▸ | RAD52 | P43351 | 5/20 | 0.58 |
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | GLA | P06280 | 2/20 | 0.56 |
| ▸ | MITF | O75030 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | TTR | P02766 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | SLC2A1 | P11166 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.53 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | NPY1R | P25929 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5452943 | 0.81 | KDM4E (0.48) | POLBKMT2ARAD52RAB9AKDM4E | |
| SCHEMBL1537966 | 0.79 | BCHE (0.67) | SLC2A1 | |
| SCHEMBL13692594 | 0.79 | BCHE (0.67) | KMT2AKDM4EMEN1SLC2A1 | |
| SCHEMBL8608662 | 0.79 | POLB (0.63) | POLBKMT2ARAD52RAB9AKDM4E | |
| SCHEMBL4980653 | 0.78 | KMT2A (0.59) | POLBKMT2ARAD52RAB9AKDM4E | |
| SCHEMBL2946229 | 0.78 | CHRM2 (0.65) | POLBKMT2ARAB9AKDM4EALDH1A1 | |
| SCHEMBL10899951 | 0.78 | KDM4E (0.44) | POLBKMT2ARAD52RAB9AKDM4E | |
| SCHEMBL7880366 | 0.78 | POLB (0.78) | POLBKMT2ARAD52RAB9AKDM4E | |
| SCHEMBL9287754 | 0.77 | SUMO3 (0.72) | KMT2ARAD52RAB9AKDM4EALDH1A1 | |
| SCHEMBL5463526 | 0.77 | KMT2A (0.54) | POLBKMT2ARAD52RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120035320-A1 | POLYACRIDINE NUCLEIC ACID DELIVERY PEPTIDE COMPLEXES | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2012-02-09 | — | — | US | claimed |
| US-20140151548-A1 | MATRIX FOR MALDI MASS SPECTROMETRY AND MALDIMASS SPECTROMETRY METHOD | KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) | 2014-06-05 | — | — | US | disclosed |
| US-20140151548-A1 | MATRIX FOR MALDI MASS SPECTROMETRY AND MALDIMASS SPECTROMETRY METHOD | KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) | 2014-06-05 | — | — | US | disclosed |
| EP-2284611-B1 | PHOTOSENSITIVE RESIN COMPOSITION, PHOTOSENSITIVE ELEMENT, RESIST PATTERN MANUFACTURING METHOD, AND PRINTED CIRCUIT BOARD MANUFACTURING METHOD | HITACHI CHEMICAL CO LTD (JP) | 2013-11-20 | — | — | EP | disclosed |
| US-8460853-B2 | Photosensitive resin composition, photosensitive element, resist pattern manufacturing method, and printed circuit board manufacturing method | HITACHI CHEMICAL COMPANY, LTD. (JP) | 2013-06-11 | — | — | US | disclosed |
| US-20120040290-A1 | PHOTOSENSITIVE RESIN COMPOSITION, AND PHOTOSENSITIVE ELEMENT, RESIST PATTERN FORMATION METHOD AND PRINTED CIRCUIT BOARD PRODUCTION METHOD EACH UTILIZING SAME | HITACHI CHEMICAL COMPANY, LTD. (JP) | 2012-02-16 | — | — | US | disclosed |
| US-20120035320-A1 | POLYACRIDINE NUCLEIC ACID DELIVERY PEPTIDE COMPLEXES | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2012-02-09 | — | — | US | disclosed |
| US-20110081616-A1 | PHOTOSENSITIVE RESIN COMPOSITION, PHOTOSENSITIVE ELEMENT, RESIST PATTERN MANUFACTURING METHOD, AND PRINTED CIRCUIT BOARD MANUFACTURING METHOD | HITACHI CHEMICAL COMPANY, LTD. (JP) | 2011-04-07 | — | — | US | disclosed |
| EP-2284611-A1 | PHOTOSENSITIVE RESIN COMPOSITION, PHOTOSENSITIVE ELEMENT, RESIST PATTERN MANUFACTURING METHOD, AND PRINTED CIRCUIT BOARD MANUFACTURING METHOD | Hitachi Chemical Company, Ltd. (JP) | 2011-02-16 | — | — | EP | disclosed |
| US-7232663-B2 | Assays employing novel substrates for measuring P450-mediated N-dealkylation | THE UNIVERSITY OF WYOMING (US) | 2007-06-19 | — | — | US | disclosed |
| US-20070015235-A1 | Assays employing novel substrates for measuring P450-mediated N-dealkylation | UNIVERSITY OF WYOMING, THE | 2007-01-18 | — | — | US | disclosed |
| US-4820714-A | QUINACRINE OR DIMETHYL D,1-2,3-DISTEAROYLOXYPROPYL-2*-HYDROXYETHYL AMMONIUM ACETATE | UNIVERSITY OF VIRGINIA ALUMNI PATENTS FOUNDATION (US) | 1989-04-11 | — | — | US | disclosed |
| US-4590277-A | BACTERICIDES, ANTITUMOR AGENTS | DEVELOPMENT FINANCE CORPORATION OF NEW ZEALAND (NZ) | 1986-05-20 | — | — | US | disclosed |
| US-4575553-A | 4'-(9-ACRIDINYLAMINO)-METHANESULFON-M-==ANISIDE | BRISTOL-MYERS COMPANY (US) | 1986-03-11 | — | — | US | disclosed |
| EP-0165592-A2 | Antitumor agents | Bristol-Myers Company (US) | 1985-12-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120035320-A1 | POLYACRIDINE NUCLEIC ACID DELIVERY PEPTIDE COMPLEXES | NUP205, PABPC1, SARNP | POLB 102/4885KMT2A 2891/4885RAD52 1538/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.