Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 6/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | GLA | P06280 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | NPY1R | P25929 | 1/20 | 0.43 |
| ▸ | SUMO3 | P55854 | 1/20 | 0.42 |
| ▸ | SUMO2 | P61956 | 1/20 | 0.42 |
| ▸ | SUMO1 | P63165 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL560210 | 0.81 | POLB (0.58) | KDM4EALDH1A1SMN1; SMN2HPGDRAB9A | |
| SCHEMBL13968056 | 0.79 | KMT2A (0.66) | KDM4EALDH1A1SMN1; SMN2HPGDKMT2A | |
| SCHEMBL12744366 | 0.78 | APP (0.55) | KDM4EALDH1A1RAB9AKMT2AMEN1 | |
| SCHEMBL14589446 | 0.78 | ALDH1A1 (0.38) | KDM4EALDH1A1SMN1; SMN2HPGDRAB9A | |
| SCHEMBL8597992 | 0.78 | KDM4E (0.45) | KDM4EALDH1A1SMN1; SMN2RAB9AKMT2A | |
| SCHEMBL1457240 | 0.78 | KDM4E (0.45) | KDM4EALDH1A1SMN1; SMN2HPGDRAB9A | |
| SCHEMBL843109 | 0.77 | KDM4E (0.49) | KDM4EALDH1A1SMN1; SMN2HPGDRAB9A | |
| SCHEMBL1456601 | 0.77 | ACHE (0.53) | KDM4EALDH1A1SMN1; SMN2HPGDRAB9A | |
| SCHEMBL31197385 | 0.77 | KDM4E (0.49) | KDM4EALDH1A1SMN1; SMN2HPGDRAB9A | |
| SCHEMBL22181050 | 0.76 | ACHE (0.55) | RAB9AKMT2APOLBRAD52ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070259881-A1 | Substituted Imidazo Ring Systems and Methods | COLEY PHARMACEUTICAL GROUP, INC. | 2007-11-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070259881-A1 | Substituted Imidazo Ring Systems and Methods | IL2, IL4, IRF3 | KDM4E 3339/4885ALDH1A1 2134/4885SMN1; SMN2 3807/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.